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6E1F

Crystal structure of the SWIRM domain of human histone lysine-specific demethylase LSD1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Lysine-specific histone demethylase 1Apolymer8910233.64UniProt (O60341)
Pfam (PF04433)
Homo sapiens (Human)BRAF35-HDAC complex protein BHC110, Flavin-containing amine oxidase domain-containing protein 2
2E, F
(A, C)
SULFATE IONnon-polymer96.12Chemie (SO4)
3G, H, I, J
(A, B, C, D)
waterwater18.0383Chemie (HOH)
Sequence modifications
A, B, C, D: 183 - 267 (UniProt: O60341)
PDBExternal DatabaseDetails
Gly 179-expression tag
Pro 180-expression tag
Gly 181-expression tag
Ser 182-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight40934.4
Non-Polymers*Number of molecules2
Total formula weight192.1
All*Total formula weight41126.5
*Water molecules are not included.

242500

PDB entries from 2025-10-01

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