6DZM
Bundibugyo virus GP (mucin-deleted) in complex with pan-ebolavirus human antibody ADI-15878 Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E, I (A, B, C) | Bundibugyo virus GP1 | polymer | 311 | 34697.9 | 3 | UniProt (B8XCN0) Pfam (PF01611) | Bundibugyo ebolavirus | Spike glycoprotein |
| 2 | B, F, J (D, E, F) | Bundibugyo virus GP2 | polymer | 177 | 19683.9 | 3 | UniProt (B8XCN0) Pfam (PF22307) | Bundibugyo ebolavirus | Spike glycoprotein |
| 3 | C, G, K (H, K, L) | Antibody ADI-15878 Fab, light chain | polymer | 106 | 11333.5 | 3 | Homo sapiens | ||
| 4 | D, H, L (G, I, J) | Antibody ADI-15878 Fab, heavy chain | polymer | 120 | 13043.6 | 3 | Homo sapiens | ||
| 5 | M, O, Q (M, O, Q) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 6 | N, P, R (N, P, R) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 3 | In PDB GlyTouCan (G22768VO) | |||
| 7 | S, T, U, V, W... (A, D, B, E, C...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) |
Sequence modifications
A, B, C: 33 - 312 (UniProt: B8XCN0)
D, E, F: 502 - 651 (UniProt: B8XCN0)
| PDB | External Database | Details |
|---|---|---|
| Ile 313 | - | expression tag |
| Asp 314 | - | expression tag |
| Ile 315 | - | expression tag |
| Ser 316 | - | expression tag |
| Glu 317 | - | expression tag |
| Ser 318 | - | expression tag |
| Thr 319 | - | expression tag |
| Glu 320 | - | expression tag |
| Pro 321 | - | expression tag |
| Gly 322 | - | expression tag |
| Pro 323 | - | expression tag |
| Leu 324 | - | expression tag |
| Thr 325 | - | expression tag |
| Asn 326 | - | expression tag |
| Thr 327 | - | expression tag |
| Thr 328 | - | expression tag |
| Arg 329 | - | expression tag |
| Gly 330 | - | expression tag |
| Ala 331 | - | expression tag |
| Ala 332 | - | expression tag |
| Asn 333 | - | expression tag |
| Leu 334 | - | expression tag |
| Leu 335 | - | expression tag |
| Thr 336 | - | expression tag |
| Gly 337 | - | expression tag |
| Ser 338 | - | expression tag |
| Arg 339 | - | expression tag |
| Arg 340 | - | expression tag |
| Thr 341 | - | expression tag |
| Arg 342 | - | expression tag |
| Arg 343 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Val 641 | - | insertion |
| Glu 642 | - | insertion |
| Val 643 | - | insertion |
| Asp 644 | Asn 641 | conflict |
| Asp 646 | Asn 643 | conflict |
| Asp 647 | Trp 644 | conflict |
| Lys 648 | Trp 645 | conflict |
| Ala 649 | Thr 646 | conflict |
| Ser 652 | - | expression tag |
| His 653 | - | expression tag |
| Pro 654 | - | expression tag |
| Gln 655 | - | expression tag |
| Phe 656 | - | expression tag |
| Glu 657 | - | expression tag |
| Lys 658 | - | expression tag |
| Gly 659 | - | expression tag |
| Gly 660 | - | expression tag |
| Gly 661 | - | expression tag |
| Ser 662 | - | expression tag |
| Gly 663 | - | expression tag |
| Gly 664 | - | expression tag |
| Gly 665 | - | expression tag |
| Ser 666 | - | expression tag |
| Gly 667 | - | expression tag |
| Gly 668 | - | expression tag |
| Gly 669 | - | expression tag |
| Ser 670 | - | expression tag |
| Trp 671 | - | expression tag |
| Ser 672 | - | expression tag |
| His 673 | - | expression tag |
| Pro 674 | - | expression tag |
| Gln 675 | - | expression tag |
| Phe 676 | - | expression tag |
| Glu 677 | - | expression tag |
| Lys 678 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 236276.6 | |
| Branched | Number of molecules | 6 |
| Total formula weight | 4005.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1327.2 | |
| All* | Total formula weight | 241609.5 |
