6DU6

Crystal structure of the pyruvate kinase (PK1) from the mosquito Aedes aegypti

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Pyruvate kinase	polymer	565	61707.7	4	UniProt (Q16F38) Pfam (PF00224) Pfam (PF02887)	Aedes aegypti (Yellowfever mosquito)
2	E, F, G, H (A, B, C, D)	1,6-di-O-phosphono-beta-D-fructofuranose	non-polymer		340.1	4	Chemie (FBP)

Sequence modifications

A, B, C, D: 1 - 529 (UniProt: Q16F38)

PDB	External Database	Details
Met -17	-	initiating methionine
Ala -16	-	expression tag
Ser -15	-	expression tag
Trp -14	-	expression tag
Ser -13	-	expression tag
His -12	-	expression tag
Pro -11	-	expression tag
Gln -10	-	expression tag
Phe -9	-	expression tag
Glu -8	-	expression tag
Lys -7	-	expression tag
Gly -6	-	expression tag
Ala -5	-	expression tag
Asp -4	-	expression tag
Asp -3	-	expression tag
Asp -2	-	expression tag
Asp -1	-	expression tag
Lys 0	-	expression tag
Pro 530	-	expression tag
Gly 531	-	expression tag
Phe 532	-	expression tag
Ser 533	-	expression tag
Ser 534	-	expression tag
Ile 535	-	expression tag
Ser 536	-	expression tag
Ala 537	-	expression tag
His 538	-	expression tag
His 539	-	expression tag
His 540	-	expression tag
His 541	-	expression tag
His 542	-	expression tag
His 543	-	expression tag
His 544	-	expression tag
His 545	-	expression tag
His 546	-	expression tag
His 547	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	246830.8
Non-Polymers*	Number of molecules	4
	Total formula weight	1360.5
All*	Total formula weight	248191.3

*Water molecules are not included.