6DTV
Crystal structure of eukaryotic DNA primase large subunit iron-sulfur cluster domain Y395F mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA primase large subunit | polymer | 197 | 23049.0 | 1 | UniProt (P20457) Pfam (PF04104) | Saccharomyces cerevisiae (Baker's yeast) | DNA polymerase alpha:primase complex p58 subunit,Pol alpha-primase complex p58 subunit,DNA primase 58 kDa subunit |
| 2 | B (A) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 1 | Chemie (SF4) | |||
| 3 | C, D (A) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 2 | Chemie (MPD) | |||
| 4 | E (A) | water | water | 18.0 | 179 | Chemie (HOH) |
Sequence modifications
A: 316 - 512 (UniProt: P20457)
| PDB | External Database | Details |
|---|---|---|
| Phe 395 | Tyr 395 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 23049.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 588.0 | |
| All* | Total formula weight | 23637.0 |
