6DT0

Cryo-EM structure of a mitochondrial calcium uniporter

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Mitochondrial calcium uniporter	polymer	458	52948.1	4	UniProt (Q7S4I4) Pfam (PF04678)	Neurospora crassa
2	E (A)	CALCIUM ION	non-polymer		40.1	1	Chemie (CA)

Sequence modifications

A, B, C, D: 46 - 493 (UniProt: Q7S4I4)

PDB	External Database	Details
Met 45	-	initiating methionine
Ala 232	Tyr 232	engineered mutation
Thr 494	-	expression tag
Asn 495	-	expression tag
Ser 496	-	expression tag
His 497	-	expression tag
His 498	-	expression tag
His 499	-	expression tag
His 500	-	expression tag
His 501	-	expression tag
His 502	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	211792.5
Non-Polymers*	Number of molecules	1
	Total formula weight	40.1
All*	Total formula weight	211832.5

*Water molecules are not included.