6DR7
YopH PTP1B WPD loop Chimera 2 PTPase bound to vanadate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Targeted effector protein | polymer | 306 | 33628.0 | 1 | UniProt (O68720) Pfam (PF00102) | Yersinia pestis | Type III secretion injected virulence protein,YopH |
| 2 | B (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 3 | C (A) | VANADATE ION | non-polymer | 114.9 | 1 | Chemie (VO4) | |||
| 4 | D (A) | water | water | 18.0 | 161 | Chemie (HOH) |
Sequence modifications
A: 164 - 468 (UniProt: O68720)
| PDB | External Database | Details |
|---|---|---|
| Met 163 | - | initiating methionine |
| Arg 235 | Cys 235 | engineered mutation |
| Thr 352 | Gly 352 | engineered mutation |
| Thr 353 | Asn 353 | engineered mutation |
| Phe 357 | Gln 357 | engineered mutation |
| Gly 358 | Thr 358 | engineered mutation |
| Val 359 | Ala 359 | engineered mutation |
| Pro 360 | Val 360 | engineered mutation |
| Glu 361 | Ser 361 | engineered mutation |
| Ala 392 | Gly 392 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33628.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 174.0 | |
| All* | Total formula weight | 33802.0 |
