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6DO5

KLHDC2 ubiquitin ligase in complex with USP1 C-end degron

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Kelch domain-containing protein 2polymer36341351.12UniProt (Q9Y2U9)
Pfam (PF13418)
Homo sapiens (Human)Hepatocellular carcinoma-associated antigen 33,Host cell factor homolog LCP,Host cell factor-like protein 1,HCLP-1
2C, D
(D, C)
USP1 C-END DEGRONpolymer6528.62UniProt (by SIFTS) (O94782)Homo sapiens
3E, F, G
(A, B, D)
waterwater18.0128Chemie (HOH)
Sequence modifications
A, B: 1 - 362 (UniProt: Q9Y2U9)
PDBExternal DatabaseDetails
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight83759.6
All*Total formula weight83759.6
*Water molecules are not included.

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PDB entries from 2025-12-17

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