6DNB
Crystal structure of T110A:S256A mutant human Glutamate oxaloacetate transaminase 1 (GOT1)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Aspartate aminotransferase, cytoplasmic | polymer | 411 | 46050.1 | 1 | UniProt (P17174) Pfam (PF00155) | Homo sapiens (Human) | cAspAT,Cysteine aminotransferase,cytoplasmic,Cysteine transaminase,cCAT,Glutamate oxaloacetate transaminase 1,Transaminase A |
| 2 | B, C (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 2 | Chemie (PG4) | |||
| 3 | D, E, F (A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 4 | G (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 5 | H (A) | water | water | 18.0 | 237 | Chemie (HOH) |
Sequence modifications
A: 3 - 413 (UniProt: P17174)
| PDB | External Database | Details |
|---|---|---|
| Ala 110 | Thr 110 | engineered mutation |
| Ala 256 | Ser 256 | engineered mutation |
| Ile 352 | Asn 352 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 46050.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 759.7 | |
| All* | Total formula weight | 46809.8 |
