6DN0

Retrofitted antibodies with stabilizing mutations: Herceptin scFv mutant with VH K30D and VL S52D.

Replaces:  4X4Y

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Human Variable Heavy Chain of Herceptin containing VH mutation K30D	polymer	136	14145.5	2		Homo sapiens
2	B, D (B, D)	Human Variable Light Chain of Herceptin containing VL mutation S52D	polymer	106	11604.8	2		Homo sapiens
3	E, F, G, H (A, B, C)	FORMIC ACID	non-polymer		46.0	4	Chemie (FMT)
4	I, J, K, L (A, B, C, D)	water	water		18.0	63	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	51500.6
Non-Polymers*	Number of molecules	4
	Total formula weight	184.1
All*	Total formula weight	51684.7

*Water molecules are not included.