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6DN0

Retrofitted antibodies with stabilizing mutations: Herceptin scFv mutant with VH K30D and VL S52D.

Replaces:  4X4Y
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, CHuman Variable Heavy Chain of Herceptin containing VH mutation K30Dpolymer13614145.52Homo sapiens
2B, DHuman Variable Light Chain of Herceptin containing VL mutation S52Dpolymer10611604.82Homo sapiens
3A, B, CFORMIC ACIDnon-polymer46.04Chemie (FMT)
4waterwater18.063Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight51500.6
Non-Polymers*Number of molecules4
Total formula weight184.1
All*Total formula weight51684.7
*Water molecules are not included.

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PDB entries from 2024-09-18

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