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6DL2

BRD4 bromodomain 1 in complex with HYB157

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Bromodomain-containing protein 4polymer12815153.41UniProt (O60885)
Pfam (PF00439)
Homo sapiens (Human)Protein HUNK1
2B
(A)
3-benzyl-2,9-dimethyl-4H,6H-thieno[2,3-e][1,2,4]triazolo[3,4-c][1,4]oxazepinenon-polymer311.41Chemie (GUJ)
3C
(A)
1,2-ETHANEDIOLnon-polymer62.11Chemie (EDO)
4D
(A)
waterwater18.0147Chemie (HOH)
Sequence modifications
A: 44 - 168 (UniProt: O60885)
PDBExternal DatabaseDetails
Ser 41-expression tag
Asn 42-expression tag
Ala 43-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight15153.4
Non-Polymers*Number of molecules2
Total formula weight373.5
All*Total formula weight15526.8
*Water molecules are not included.

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PDB entries from 2025-12-03

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