6DK1
Human sigma-1 receptor bound to (+)-pentazocine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Sigma non-opioid intracellular receptor 1 | polymer | 227 | 25447.9 | 3 | UniProt (Q99720) Pfam (PF04622) | Homo sapiens (Human) | Aging-associated gene 8 protein,SR31747-binding protein,SR-BP,Sigma 1-type opioid receptor,hSigmaR1 |
| 2 | D, O, X (A, B, C) | (2S,6S,11S)-6,11-dimethyl-3-(3-methylbut-2-en-1-yl)-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-8-ol | non-polymer | 285.4 | 3 | Chemie (GM4) | |||
| 3 | AA, E, F, G, H... (C, A, B) | SULFATE ION | non-polymer | 96.1 | 14 | Chemie (SO4) | |||
| 4 | BA, CA, L, T (C, A, B) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 5 | DA, EA, FA, GA, HA... (C, A, B) | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate | non-polymer | 356.5 | 11 | Chemie (OLC) | |||
| 6 | JA, KA, LA (A, B, C) | water | water | 18.0 | 86 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 223 (UniProt: Q99720)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 76343.6 | |
| Non-Polymers* | Number of molecules | 32 |
| Total formula weight | 6491.5 | |
| All* | Total formula weight | 82835.1 |
