6DK1
Human sigma-1 receptor bound to (+)-pentazocine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Sigma non-opioid intracellular receptor 1 | polymer | 227 | 25447.9 | 3 | UniProt (Q99720) Pfam (PF04622) | Homo sapiens (Human) | Aging-associated gene 8 protein,SR31747-binding protein,SR-BP,Sigma 1-type opioid receptor,hSigmaR1 |
| 2 | D, O, X (A, B, C) | (2S,6S,11S)-6,11-dimethyl-3-(3-methylbut-2-en-1-yl)-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-8-ol | non-polymer | 285.4 | 3 | Chemie (GM4) PubChem (9669) PubChem (66387) PubChem (198520) PubChem (441278) PubChem (6102288) PubChem (6328623) PubChem (11000612) PubChem (12259677) PubChem (12259678) PubChem (12259680) PubChem (12259682) PubChem (12259685) PubChem (25234108) PubChem (44303090) PubChem (45055403) PubChem (44246749) PubChem (4736) PubChem (91259853) PubChem (12259681) PubChem (58506875) PubChem (90679108) | |||
| 3 | AA, E, F, G, H... (C, A, B) | SULFATE ION | non-polymer | 96.1 | 14 | Chemie (SO4) | |||
| 4 | BA, CA, L, T (C, A, B) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) PubChem (753) | |||
| 5 | DA, EA, FA, GA, HA... (C, A, B) | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate | non-polymer | 356.5 | 11 | Chemie (OLC) PubChem (5283468) PubChem (5364833) PubChem (11451146) PubChem (12178130) PubChem (25021708) PubChem (46840179) PubChem (54294270) PubChem (33022) PubChem (54294271) | |||
| 6 | JA, KA, LA (A, B, C) | water | water | 18.0 | 86 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 223 (UniProt: Q99720)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 76343.6 | |
| Non-Polymers* | Number of molecules | 32 |
| Total formula weight | 6491.5 | |
| All* | Total formula weight | 82835.1 |
