6DJP

Integrin alpha-v beta-8 in complex with the Fabs 8B8 and 68

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Integrin alpha-v	polymer	965	106758.3	1	UniProt (P06756) Pfam (PF01839) Pfam (PF08441) Pfam (PF20805) Pfam (PF20806)	Homo sapiens (Human)	Vitronectin receptor,Vitronectin receptor subunit alpha
2	B (B)	Integrin beta-8	polymer	639	70837.2	1	UniProt (P26012) Pfam (PF17205) Pfam (PF00362) Pfam (PF07974)	Homo sapiens (Human)
3	C (C)	8B8 heavy chain Fab	polymer	213	23314.8	1		Mus musculus (Mouse)
4	D (D)	8B8 light chain Fab	polymer	213	23241.6	1		Mus musculus (Mouse)
5	E (E)	68 heavy chain Fab	polymer	212	22680.3	1		Mus musculus (Mouse)
6	F (F)	68 light chain Fab	polymer	214	23420.8	1		Mus musculus (Mouse)
7	G, H, J, K, L... (G, H, J, K, L...)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	6	In PDB GlyTouCan (G42666HT)
8	I (I)	alpha-D-mannopyranose-(1-4)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1073.0	1	In PDB GlyTouCan (G34220DL)
9	N (N)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G15407YE)
10	O, P (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	270253.0
Branched	Number of molecules	8
	Total formula weight	4205.9
Non-Polymers*	Number of molecules	2
	Total formula weight	442.4
All*	Total formula weight	274901.3

*Water molecules are not included.