6DJI

Crystal structure of Tdp1 catalytic domain in complex with compound XZ522

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Tyrosyl-DNA phosphodiesterase 1	polymer	461	52126.3	2	UniProt (Q9NUW8) Pfam (PF06087)	Homo sapiens (Human)	Tyr-DNA phosphodiesterase 1
2	C, H (A, B)	3-hydroxybenzene-1,2-dicarboxylic acid	non-polymer		182.1	2	Chemie (GOG)
3	D, E, F, G, I... (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	6	Chemie (EDO)
4	K, L (A, B)	water	water		18.0	779	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	104252.7
Non-Polymers*	Number of molecules	8
	Total formula weight	736.7
All*	Total formula weight	104989.3

*Water molecules are not included.