6DJ3

Crystal structure of CNNM2 cyclic nucleotide-binding homology domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Metal transporter CNNM2	polymer	199	22727.1	2	UniProt (Q9H8M5)	Homo sapiens (Human)	Ancient conserved domain-containing protein 2,Cyclin-M2
2	C, D, E (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	3	Chemie (EDO)
3	F, G (A, B)	water	water		18.0	23	Chemie (HOH)

Sequence modifications

A, B: 585 - 722 (UniProt: Q9H8M5)

PDB	External Database	Details
Gly 580	-	expression tag
Pro 581	-	expression tag
Leu 582	-	expression tag
Gly 583	-	expression tag
Ser 584	-	expression tag

A, B: 768 - 822 (UniProt: Q9H8M5)

PDB	External Database	Details
Val 767	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	45454.2
Non-Polymers*	Number of molecules	3
	Total formula weight	186.2
All*	Total formula weight	45640.4

*Water molecules are not included.