6DIG
Crystal structure of DQA1*01:02/DQB1*06:02 in complex with a hypocretin peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | MHC class II HLA-DQ-alpha chain | polymer | 207 | 23205.9 | 1 | UniProt (Q30066) Pfam (PF00993) Pfam (PF07654) | Homo sapiens (Human) | |
| 2 | B (B) | HLA class II histocompatibility antigen, DQ beta 1 chain | polymer | 215 | 24391.1 | 1 | UniProt (Q5SU54) Pfam (PF00969) Pfam (PF07654) | Homo sapiens (Human) | MHC class II antigen |
| 3 | C (C) | 13-mer peptide: ALA-GLY-ASN-HIS-ALA-ALA-GLY-ILE-LEU-THR-LEU-GLY-LYS | polymer | 13 | 1224.4 | 1 | Homo sapiens (human) | ||
| 4 | D (D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 5 | E, F (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 6 | G (A) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 7 | H, I, J (A, B, C) | water | water | 18.0 | 272 | Chemie (HOH) |
Sequence modifications
A: 1 - 196 (UniProt: Q30066)
B: 3 - 198 (UniProt: Q5SU54)
| PDB | External Database | Details |
|---|---|---|
| Gly 197 | - | expression tag |
| Gly 198 | - | expression tag |
| Gly 199 | - | expression tag |
| Gly 200 | - | expression tag |
| Ser 201 | - | expression tag |
| Leu 202 | - | expression tag |
| Glu 203 | - | expression tag |
| Val 204 | - | expression tag |
| Leu 205 | - | expression tag |
| Phe 206 | - | expression tag |
| Gln 207 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Gly 1 | - | expression tag |
| Gly 2 | - | expression tag |
| Gly 199 | - | expression tag |
| Thr 200 | - | expression tag |
| Gly 201 | - | expression tag |
| Gly 202 | - | expression tag |
| Gly 203 | - | expression tag |
| Gly 204 | - | expression tag |
| Ser 205 | - | expression tag |
| Leu 206 | - | expression tag |
| Glu 207 | - | expression tag |
| Val 208 | - | expression tag |
| Leu 209 | - | expression tag |
| Phe 210 | - | expression tag |
| Gln 211 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 48821.4 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 564.6 | |
| All* | Total formula weight | 49810.4 |
