6DIA
DNA polymerase beta substrate complex with templating cytosine and incoming Fapy-dGTP analog
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA polymerase beta | polymer | 335 | 38241.7 | 1 | UniProt (P06746) Pfam (PF14716) Pfam (PF10391) Pfam (PF14792) Pfam (PF14791) | Homo sapiens (Human) | |
| 2 | B (T) | DNA (5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3') | polymer | 16 | 4829.1 | 1 | synthetic construct | ||
| 3 | C (P) | DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3') | polymer | 10 | 3061.0 | 1 | synthetic construct | ||
| 4 | D (D) | DNA (5'-D(P*GP*TP*CP*GP*G)-3') | polymer | 5 | 1536.0 | 1 | synthetic construct | ||
| 5 | E (A) | 1-[2-amino-5-(formylamino)-6-oxo-1,6-dihydropyrimidin-4-yl]-2,5-anhydro-1,3-dideoxy-6-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-D-ribo-hexitol | non-polymer | 524.2 | 1 | Chemie (GKS) | |||
| 6 | F, J (A, P) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 7 | G, H, I (A, T) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 8 | K, L, M, N (A, T, P, D) | water | water | 18.0 | 375 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 47667.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 690.4 | |
| All* | Total formula weight | 48358.3 |
