6DH8
Crystal structure of HIV-1 Protease NL4-3 I50V Mutant in complex with UMass6
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | B, A | Protease | polymer | 99 | 10817.8 | 2 | UniProt (Q8ULI3) Pfam (PF00077) UniProt (by SIFTS) (Q7ZCR0) In PDB | Human immunodeficiency virus 1 | |
| 2 | A | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 3 | A | (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(1S,2R)-3-{[(4-aminophenyl)sulfonyl](2-ethylbutyl)amino}-1-benzyl-2-hydroxypropyl]carbamate | non-polymer | 575.7 | 1 | Chemie (A60) | |||
| 4 | water | water | 18.0 | 223 | Chemie (HOH) |
Sequence modifications
B, A: 1 - 99 (UniProt: Q8ULI3)
| PDB | External Database | Details |
|---|---|---|
| Lys 7 | Gln 7 | engineered mutation |
| Val 50 | Ile 50 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21635.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 960.0 | |
| All* | Total formula weight | 22595.6 |
