6DH4
Crystal structure of HIV-1 Protease NL4-3 V82I Mutant in complex with UMass1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | Protease | polymer | 99 | 10845.9 | 2 | UniProt (Q6B6C5) Pfam (PF00077) | Human immunodeficiency virus 1 | |
| 2 | C, D, E (A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 3 | F (A) | (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(1S,2R)-3-{[(4-aminophenyl)sulfonyl][(2S)-2-methylbutyl]amino}-1-benzyl-2-hydroxypropyl]carbamate | non-polymer | 561.7 | 1 | Chemie (K13) | |||
| 4 | G, H (B, A) | water | water | 18.0 | 169 | Chemie (HOH) |
Sequence modifications
B, A: 1 - 99 (UniProt: Q6B6C5)
| PDB | External Database | Details |
|---|---|---|
| Lys 7 | Gln 7 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21691.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 849.9 | |
| All* | Total formula weight | 22541.6 |
