6DH0
Crystal structure of HIV-1 Protease NL4-3 I84V Mutant in complex with darunavir
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | B, A | Protease | polymer | 99 | 10817.8 | 2 | UniProt (Q7ZCI0) Pfam (PF00077) In PDB | Human immunodeficiency virus 1 | |
| 2 | A | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE | non-polymer | 547.7 | 1 | Chemie (017) | |||
| 3 | water | water | 18.0 | 156 | Chemie (HOH) |
Sequence modifications
B, A: 1 - 99 (UniProt: Q7ZCI0)
| PDB | External Database | Details |
|---|---|---|
| Lys 7 | Gln 7 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21635.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 547.7 | |
| All* | Total formula weight | 22183.3 |
