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6DGL

Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with Darglitazone

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BPeroxisome proliferator-activated receptor gammapolymer27631506.62UniProt (P37231)
Pfam (PF00104)
In PDB
Homo sapiens (Human)PPAR-gamma,Nuclear receptor subfamily 1 group C member 3
2A, B(5Z)-5-({4-[3-(5-methyl-2-phenyl-1,3-oxazol-4-yl)propanoyl]phenyl}methylidene)-1,3-thiazolidine-2,4-dionenon-polymer418.52Chemie (GEV)
3waterwater18.0423Chemie (HOH)
Sequence modifications
A, B: 203 - 477 (UniProt: P37231)
PDBExternal DatabaseDetails
Gly 202-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight63013.1
Non-Polymers*Number of molecules2
Total formula weight836.9
All*Total formula weight63850.1
*Water molecules are not included.

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PDB entries from 2024-07-17

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