6DGL
Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with Darglitazone
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Peroxisome proliferator-activated receptor gamma | polymer | 276 | 31506.6 | 2 | UniProt (P37231) Pfam (PF00104) | Homo sapiens (Human) | PPAR-gamma,Nuclear receptor subfamily 1 group C member 3 |
| 2 | C, D (A, B) | (5Z)-5-({4-[3-(5-methyl-2-phenyl-1,3-oxazol-4-yl)propanoyl]phenyl}methylidene)-1,3-thiazolidine-2,4-dione | non-polymer | 418.5 | 2 | Chemie (GEV) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 423 | Chemie (HOH) |
Sequence modifications
A, B: 203 - 477 (UniProt: P37231)
| PDB | External Database | Details |
|---|---|---|
| Gly 202 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 63013.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 836.9 | |
| All* | Total formula weight | 63850.1 |
