6DFG
BG505 MD39 SOSIP trimer in complex with mature BG18 fragment antigen binding
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E, I (A, C, D) | Envelope glycoprotein gp160 | polymer | 476 | 53302.3 | 3 | UniProt (Q2N0S6) Pfam (PF00516) | Human immunodeficiency virus 1 | Env polyprotein |
| 2 | B, F, J (B, E, F) | Envelope glycoprotein gp160 | polymer | 162 | 18250.5 | 3 | UniProt (Q2N0S8) Pfam (PF00517) | Human immunodeficiency virus 1 | Env polyprotein |
| 3 | C, G, K (H, G, I) | mature BG18 fragment antigen binding heavy chain | polymer | 233 | 25043.2 | 3 | Homo sapiens | ||
| 4 | D, H, L (L, J, K) | mature BG18 fragment antigen binding light chain | polymer | 214 | 22937.4 | 3 | Homo sapiens | ||
| 5 | GA, M, W (g, M, W) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 3 | In PDB GlyTouCan (G81315DD) | |||
| 6 | AA, DA, FA, HA, IA... (a, d, f, h, i...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 15 | In PDB GlyTouCan (G42666HT) | |||
| 7 | JA, P, Z (j, P, Z) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 3 | In PDB GlyTouCan (G56014GC) | |||
| 8 | BA, LA, R (b, l, R) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
| 9 | CA, MA, S (c, m, S) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1721.5 | 3 | In PDB GlyTouCan (G40702WU) | |||
| 10 | EA, OA, U (e, o, U) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 3 | In PDB GlyTouCan (G01760ZU) | |||
| 11 | AB, BB, CB, DB, EB... (C, G, D, I, A...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 18 | Chemie (NAG) |
Sequence modifications
A, C, D: 31 - 508 (UniProt: Q2N0S6)
B, E, F: 512 - 664 (UniProt: Q2N0S8)
| PDB | External Database | Details |
|---|---|---|
| Glu 106 | Thr 105 | conflict |
| Ile 271 | Met 270 | conflict |
| Leu 288 | Phe 287 | conflict |
| Val 304 | Arg 303 | conflict |
| Tyr 319 | Ala 316 | conflict |
| Asn 332 | Thr 330 | conflict |
| Gln 363 | Asn 361 | conflict |
| Cys 501 | Ala 498 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ser 519 | Phe 518 | conflict |
| Pro 559 | Ile 558 | conflict |
| Pro 561 | Ala 560 | conflict |
| Asp 568 | Leu 567 | conflict |
| His 570 | Val 569 | conflict |
| His 585 | Arg 584 | conflict |
| Cys 605 | Thr 604 | conflict |
| Gly 665 | - | expression tag |
| Thr 666 | - | expression tag |
| Lys 667 | - | expression tag |
| His 668 | - | expression tag |
| His 669 | - | expression tag |
| His 670 | - | expression tag |
| His 671 | - | expression tag |
| His 672 | - | expression tag |
| His 673 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 358600.2 | |
| Branched | Number of molecules | 30 |
| Total formula weight | 21974.1 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 3981.7 | |
| All* | Total formula weight | 384556.0 |
