6DDQ
Crystal structure of the double mutant (R39Q/D52N) of the full-length NT5C2 in the basal state
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Cytosolic purine 5'-nucleotidase | polymer | 579 | 66926.7 | 2 | UniProt (P49902) Pfam (PF05761) In PDB | Homo sapiens (Human) | Cytosolic 5'-nucleotidase II |
2 | A, B | PHOSPHATE ION | non-polymer | 95.0 | 4 | Chemie (PO4) | |||
3 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
4 | water | water | 18.0 | 780 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 561 (UniProt: P49902)
PDB | External Database | Details |
---|---|---|
Gly -17 | - | expression tag |
Ser -16 | - | expression tag |
Ser -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
Ser -8 | - | expression tag |
Ser -7 | - | expression tag |
Gly -6 | - | expression tag |
Leu -5 | - | expression tag |
Val -4 | - | expression tag |
Pro -3 | - | expression tag |
Arg -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Gln 39 | Arg 39 | engineered mutation |
Asn 52 | Asp 52 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 133853.3 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 504.0 | |
All* | Total formula weight | 134357.4 |