6DDC

Crystal structure of the single mutant (D52N) of NT5C2-537X in the basal state, Northeast Structural Genomics Consortium Target

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Cytosolic purine 5'-nucleotidase	polymer	554	63956.8	2	UniProt (P49902) Pfam (PF05761)	Homo sapiens (Human)	Cytosolic 5'-nucleotidase II
2	C, F (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
3	D, E, G, H (A, B)	PHOSPHATE ION	non-polymer		95.0	4	Chemie (PO4)
4	I, J (A, B)	water	water		18.0	275	Chemie (HOH)

Sequence modifications

A, B: 1 - 536 (UniProt: P49902)

PDB	External Database	Details
Gly -17	-	expression tag
Ser -16	-	expression tag
Ser -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
Ser -8	-	expression tag
Ser -7	-	expression tag
Gly -6	-	expression tag
Leu -5	-	expression tag
Val -4	-	expression tag
Pro -3	-	expression tag
Arg -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Asn 52	Asp 52	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	127913.5
Non-Polymers*	Number of molecules	6
	Total formula weight	428.5
All*	Total formula weight	128342.0

*Water molecules are not included.