6DB4
JAK3 with Cyanamide CP34
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Tyrosine-protein kinase JAK3 | polymer | 321 | 36543.7 | 1 | UniProt (P52333) Pfam (PF07714) In PDB | Homo sapiens (Human) | Janus kinase 3,JAK-3,Leukocyte janus kinase,L-JAK |
2 | A | N-[(1S)-6-(5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]imidoformamide | non-polymer | 353.4 | 1 | Chemie (G4Y) | |||
3 | water | water | 18.0 | 294 | Chemie (HOH) |
Sequence modifications
A: 812 - 1124 (UniProt: P52333)
PDB | External Database | Details |
---|---|---|
Met 804 | - | expression tag |
Gly 805 | - | expression tag |
His 806 | - | expression tag |
His 807 | - | expression tag |
His 808 | - | expression tag |
His 809 | - | expression tag |
His 810 | - | expression tag |
His 811 | - | expression tag |
Ser 1048 | Cys 1048 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 36543.7 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 353.4 | |
All* | Total formula weight | 36897.1 |