6D9X
Discovery of Potent 2-Aryl-6,7-Dihydro-5HPyrrolo[ 1,2-a]imidazoles as WDR5 WIN-site Inhibitors Using Fragment-Based Methods and Structure-Based Design
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | WD repeat-containing protein 5 | polymer | 313 | 34391.0 | 1 | UniProt (P61964) Pfam (PF00400) | Homo sapiens (Human) | BMP2-induced 3-kb gene protein |
| 2 | B (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 3 | C (A) | 2-phenyl-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole | non-polymer | 184.2 | 1 | Chemie (FZM) | |||
| 4 | D (A) | water | water | 18.0 | 84 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34391.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 207.2 | |
| All* | Total formula weight | 34598.2 |
