6D9J

Mammalian 80S ribosome with a double translocated CrPV-IRES, P-sitetRNA and eRF1.

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	uL2	polymer	257	28088.9	1	UniProt (G1TT27) Pfam (PF00181) Pfam (PF03947) In PDB	Oryctolagus cuniculus (Rabbit)
2	B	uL3	polymer	403	46104.9	1	UniProt (G1TL06) Pfam (PF00297) In PDB	Oryctolagus cuniculus (Rabbit)
3	C	uL4	polymer	392	44232.2	1	UniProt (G1SVW5) Pfam (PF14374) Pfam (PF00573) In PDB	Oryctolagus cuniculus (Rabbit)
4	D	uL18	polymer	297	34479.8	1	UniProt (G1SYJ6) UniProt (by SIFTS) (P19949) In PDB	Oryctolagus cuniculus (Rabbit)
5	E	eL6	polymer	291	33028.3	1	UniProt (G1SKF7) Pfam (PF03868) Pfam (PF01159) In PDB	Oryctolagus cuniculus (Rabbit)
6	F	uL30	polymer	249	29514.3	1	UniProt (G1SV32) Pfam (PF08079) Pfam (PF00327) In PDB	Oryctolagus cuniculus (Rabbit)
7	G	eL8	polymer	242	27655.8	1	UniProt (G1STW0) Pfam (PF01248) In PDB	Oryctolagus cuniculus (Rabbit)
8	H	uL6	polymer	192	21871.4	1	UniProt (G1TX33) Pfam (PF00347) UniProt (by SIFTS) (G1SWI6) In PDB	Oryctolagus cuniculus (Rabbit)
9	I	uL16	polymer	214	24643.1	1	UniProt (B7NZQ2) Pfam (PF00252) In PDB	Oryctolagus cuniculus (Rabbit)	Ribosomal protein L10 (Predicted)
10	J	uL11	polymer	178	20288.5	1	UniProt (G1TUB8) Pfam (PF00281) Pfam (PF00673) In PDB	Oryctolagus cuniculus (Rabbit)
11	L	eL13	polymer	211	24331.7	1	UniProt (G1TPV0) In PDB	Oryctolagus cuniculus (Rabbit)
12	M	eL14	polymer	198	21950.3	1	UniProt (U3KNW6) Pfam (PF01929) UniProt (by SIFTS) (G1SZ12) In PDB	Oryctolagus cuniculus (Rabbit)
13	N	eL15	polymer	204	24207.3	1	UniProt (G1T0C1) Pfam (PF00827) In PDB	Oryctolagus cuniculus (Rabbit)
14	O	uL13	polymer	198	23047.7	1		Oryctolagus cuniculus (Rabbit)
15	P	uL22	polymer	187	21741.6	1	UniProt (G1TVT6) Pfam (PF00237) UniProt (by SIFTS) (G1SCJ6) In PDB	Oryctolagus cuniculus (Rabbit)
16	Q	eL18	polymer	187	21568.5	1		Oryctolagus cuniculus (Rabbit)
17	R	eL19	polymer	181	21744.2	1		Oryctolagus cuniculus (Rabbit)
18	S	eL20	polymer	176	20827.6	1		Oryctolagus cuniculus (Rabbit)
19	T	eL21	polymer	160	18610.0	1	UniProt (G1SHQ2) Pfam (PF01157) In PDB	Oryctolagus cuniculus (Rabbit)
20	U	eL22	polymer	99	11495.3	1		Oryctolagus cuniculus (Rabbit)
21	V	uL14	polymer	140	14892.5	1	UniProt (G1T6D1) Pfam (PF00238) In PDB	Oryctolagus cuniculus (Rabbit)
22	W	eL24	polymer	157	17825.1	1	UniProt (G1SE28) Pfam (PF01246) In PDB	Oryctolagus cuniculus (Rabbit)
23	X	eL23	polymer	156	17768.2	1	UniProt (G1SE76) Pfam (PF03939) Pfam (PF00276) In PDB	Oryctolagus cuniculus (Rabbit)
24	Y	uL24	polymer	145	17303.4	1	UniProt (G1SQH0) Pfam (PF16906) Pfam (PF00467) In PDB	Oryctolagus cuniculus (Rabbit)
25	Z	eL27	polymer	136	15835.8	1	UniProt (G1TXF6) Pfam (PF00467) Pfam (PF01777) In PDB	Oryctolagus cuniculus (Rabbit)
26	a	uL15	polymer	148	16617.5	1	UniProt (G1SNY0) Pfam (PF00828) In PDB	Oryctolagus cuniculus (Rabbit)
27	b	eL29	polymer	226	24931.6	1	UniProt (G1SGR6) Pfam (PF01779) In PDB	Oryctolagus cuniculus (Rabbit)
28	c	eL30	polymer	115	12807.1	1	UniProt (G1TDL2) Pfam (PF01248) In PDB	Oryctolagus cuniculus (Rabbit)
29	d	eL31	polymer	125	14494.9	1	UniProt (G1SHG0) Pfam (PF01198) In PDB	Oryctolagus cuniculus (Rabbit)
30	e	eL32	polymer	135	15898.9	1	UniProt (G1U437) Pfam (PF01655) UniProt (by SIFTS) (G1TUN8) In PDB	Oryctolagus cuniculus (Rabbit)
31	f	eL33	polymer	110	12580.8	1	UniProt (G1SF08) Pfam (PF01247) In PDB	Oryctolagus cuniculus (Rabbit)
32	g	eL34	polymer	126	14210.1	1	UniProt (G1U945) Pfam (PF01199) UniProt (by SIFTS) (G1TXG5) In PDB	Oryctolagus cuniculus (Rabbit)
33	h	eL35	polymer	123	14566.6	1	UniProt (G1SIT5) Pfam (PF00831) In PDB	Oryctolagus cuniculus (Rabbit)
34	i	eL36	polymer	105	12263.8	1	UniProt (G1TTQ5) Pfam (PF01158) In PDB	Oryctolagus cuniculus (Rabbit)
35	j	eL37	polymer	97	11111.0	1	UniProt (U3KPD5) Pfam (PF01907) In PDB	Oryctolagus cuniculus (Rabbit)
36	k	eL38	polymer	69	8107.8	1		Oryctolagus cuniculus (Rabbit)
37	l	eL39	polymer	51	6455.8	1	UniProt (G1TTN1) Pfam (PF00832) In PDB	Oryctolagus cuniculus (Rabbit)
38	m	eL40	polymer	52	6199.6	1		Oryctolagus cuniculus (Rabbit)
39	n	eL41	polymer	25	3473.5	1		Oryctolagus cuniculus (Rabbit)
40	o	eL42	polymer	106	12477.0	1	UniProt (G1U344) Pfam (PF00935) UniProt (by SIFTS) (G1T040) In PDB	Oryctolagus cuniculus (Rabbit)
41	p	eL43	polymer	92	10299.4	1	UniProt (G1SY53) Pfam (PF01780) In PDB	Oryctolagus cuniculus (Rabbit)
42	r	eL28	polymer	137	15783.6	1	UniProt (G1U7L1) Pfam (PF01778) In PDB	Oryctolagus cuniculus (Rabbit)
43	s	uL10	polymer	303	33270.5	1	UniProt (G1U6N2) In PDB	Oryctolagus cuniculus (Rabbit)
44	t	uL11	polymer	195	21295.6	1	UniProt (G1SMR7) Pfam (PF03946) Pfam (PF00298) In PDB	Oryctolagus cuniculus (Rabbit)
45	5	28S rRNA	polymer	3594	1164731.9	1		Oryctolagus cuniculus (Rabbit)
46	7	5S rRNA	polymer	119	38385.8	1	REF (1304938343)	Oryctolagus cuniculus (Rabbit)
47	8	5.8S rRNA	polymer	151	48545.7	1		Oryctolagus cuniculus (Rabbit)
48	K	uL1	polymer	217	24879.4	1	UniProt (G1SKZ8) Pfam (PF00687) In PDB	Oryctolagus cuniculus (Rabbit)
49	2	18S rRNA	polymer	1697	547733.1	1		Oryctolagus cuniculus (Rabbit)
50	BB	uS2	polymer	217	24361.9	1		Oryctolagus cuniculus (Rabbit)
51	CC	eS1	polymer	264	30002.1	1	UniProt (G1SS70) Pfam (PF01015) In PDB	Oryctolagus cuniculus (Rabbit)
52	DD	uS5	polymer	221	24441.8	1		Oryctolagus cuniculus (Rabbit)
53	EE	uS3	polymer	281	31146.6	1	UniProt (G1TNM3) Pfam (PF07650) Pfam (PF00189) In PDB	Oryctolagus cuniculus (Rabbit)
54	FF	eS4	polymer	262	29523.7	1		Oryctolagus cuniculus (Rabbit)
55	GG	uS7	polymer	204	22913.5	1	UniProt (G1TFM5) Pfam (PF00177) In PDB	Oryctolagus cuniculus (Rabbit)
56	HH	eS6	polymer	249	28751.9	1	UniProt (G1TM55) Pfam (PF01092) In PDB	Oryctolagus cuniculus (Rabbit)
57	II	eS7	polymer	194	22168.9	1	UniProt (G1SVB0) In PDB	Oryctolagus cuniculus (Rabbit)
58	JJ	eS8	polymer	206	24003.0	1	UniProt (G1TJW1) Pfam (PF01201) In PDB	Oryctolagus cuniculus (Rabbit)
59	KK	uS4	polymer	194	22641.6	1	UniProt (B7NZS8) Pfam (PF00163) Pfam (PF01479) In PDB	Oryctolagus cuniculus (Rabbit)
60	LL	eS10	polymer	149	17156.9	1	UniProt (G1U0Y5) Pfam (PF03501) In PDB	Oryctolagus cuniculus (Rabbit)
61	MM	uS17	polymer	158	18468.8	1	UniProt (G1TRM4) Pfam (PF16205) Pfam (PF00366) In PDB	Oryctolagus cuniculus (Rabbit)
62	NN	eS12	polymer	132	14539.0	1	UniProt (G1SFR8) Pfam (PF01248) In PDB	Oryctolagus cuniculus (Rabbit)
63	OO	uS15	polymer	151	17259.4	1	UniProt (G1SP51) Pfam (PF08069) Pfam (PF00312) In PDB	Oryctolagus cuniculus (Rabbit)
64	PP	uS11	polymer	151	16302.8	1	UniProt (G1U472) Pfam (PF00411) UniProt (by SIFTS) (G1T1F0) In PDB	Oryctolagus cuniculus (Rabbit)
65	QQ	uS19	polymer	145	17049.2	1	UniProt (G1U0Q2) Pfam (PF00203) In PDB	Oryctolagus cuniculus (Rabbit)
66	RR	uS9	polymer	172	19213.5	1	UniProt (G1SGX4) Pfam (PF00380) In PDB	Oryctolagus cuniculus (Rabbit)
67	SS	eS17	polymer	135	15552.1	1	UniProt (G1TU13) Pfam (PF00833) In PDB	Oryctolagus cuniculus (Rabbit)
68	TT	uS13	polymer	152	17759.8	1	UniProt (G1TPG3) Pfam (PF00416) In PDB	Oryctolagus cuniculus (Rabbit)
69	UU	eS19	polymer	145	16235.8	1	UniProt (G1TN62) Pfam (PF01090) In PDB	Oryctolagus cuniculus (Rabbit)
70	VV	uS10	polymer	119	13398.8	1	UniProt (G1SIZ2) Pfam (PF00338) In PDB	Oryctolagus cuniculus (Rabbit)
71	WW	eS21	polymer	83	9124.4	1		Oryctolagus cuniculus (Rabbit)
72	XX	uS8	polymer	130	14865.6	1	UniProt (G1TG89) Pfam (PF00410) In PDB	Oryctolagus cuniculus (Rabbit)
73	YY	uS12	polymer	143	15784.5	1	UniProt (G1SZ47) Pfam (PF00164) In PDB	Oryctolagus cuniculus (Rabbit)
74	ZZ	eS24	polymer	134	15548.4	1	UniProt (G1T3D8) Pfam (PF01282) In PDB	Oryctolagus cuniculus (Rabbit)
75	aa	eS25	polymer	125	13776.2	1	UniProt (G1TDB3) Pfam (PF03297) In PDB	Oryctolagus cuniculus (Rabbit)
76	bb	eS26	polymer	101	11645.8	1		Oryctolagus cuniculus (Rabbit)
77	cc	eS27	polymer	84	9480.2	1	UniProt (G1TZ76) Pfam (PF01667) In PDB	Oryctolagus cuniculus (Rabbit)
78	dd	eS28	polymer	69	7855.1	1	UniProt (G1TIB4) Pfam (PF01200) In PDB	Oryctolagus cuniculus (Rabbit)
79	ee	eS29	polymer	56	6690.8	1		Oryctolagus cuniculus (Rabbit)
80	ff	eS30	polymer	133	14498.9	1	UniProt (G1T8A2) Pfam (PF00240) Pfam (PF04758) In PDB	Oryctolagus cuniculus (Rabbit)
81	gg	eS31	polymer	156	18004.0	1	UniProt (G1SK22) Pfam (PF00240) Pfam (PF01599) In PDB	Oryctolagus cuniculus (Rabbit)
82	hh	RACK1	polymer	317	35115.7	1	UniProt (G1SJB4) Pfam (PF00400) In PDB	Oryctolagus cuniculus (Rabbit)
83	3	P-site tRNA	polymer	87	28094.6	1	GenBank (1370526512)	Escherichia coli
84	9	eEF2	polymer	856	95232.9	1	UniProt (P13639) Pfam (PF00009) Pfam (PF03144) Pfam (PF14492) Pfam (PF03764) Pfam (PF00679) In PDB	Homo sapiens (Human)	EF-2
85	4	CrPV IRES	polymer	190	60789.8	1	GenBank (8895506)	Cricket paralysis virus
86	p, 2, bb, gg	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
87	5	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)

Sequence modifications

L: 1 - 211 (UniProt: G1TPV0)

PDB	External Database	Details
Ile 46	-	insertion
Ala 47	-	insertion
Pro 48	-	insertion
Arg 49	-	insertion
Pro 50	-	insertion
Ala 51	-	insertion
Ala 52	-	insertion
Gly 53	-	insertion
Pro 54	-	insertion

JJ: 2 - 207 (UniProt: G1TJW1)

PDB	External Database	Details
Arg 47	Gly 47	conflict

4: 6030 - 6216 (GenBank: 8895506)

PDB	External Database	Details
C 6217	-	insertion
U 6218	-	insertion
U 6219	-	insertion

Contents of the asymmetric unit

Polymers	Number of chains	85
	Total formula weight	3493574.9
Non-Polymers*	Number of molecules	6
	Total formula weight	310.2
All*	Total formula weight	3493885.1

*Water molecules are not included.