6D9J
Mammalian 80S ribosome with a double translocated CrPV-IRES, P-sitetRNA and eRF1.
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ribosomal protein L8 | polymer | 257 | 28088.9 | 1 | UniProt (G1TT27) Pfam (PF00181) Pfam (PF03947) | Oryctolagus cuniculus (rabbit) | |
| 2 | B (B) | uL3 | polymer | 403 | 46104.9 | 1 | UniProt (G1TL06) Pfam (PF00297) | Oryctolagus cuniculus (rabbit) | |
| 3 | C (C) | Ribosomal protein L4 | polymer | 392 | 44232.2 | 1 | UniProt (G1SVW5) Pfam (PF14374) Pfam (PF00573) | Oryctolagus cuniculus (rabbit) | |
| 4 | D (D) | Large ribosomal subunit protein uL18 | polymer | 297 | 34479.8 | 1 | UniProt (P19949) | Oryctolagus cuniculus (rabbit) | 60S ribosomal protein L5 |
| 5 | E (E) | 60S ribosomal protein L6 | polymer | 291 | 33028.3 | 1 | UniProt (G1SKF7) Pfam (PF03868) Pfam (PF01159) | Oryctolagus cuniculus (rabbit) | |
| 6 | F (F) | uL30 | polymer | 249 | 29514.3 | 1 | UniProt (G1SV32) Pfam (PF08079) Pfam (PF00327) | Oryctolagus cuniculus (rabbit) | |
| 7 | G (G) | eL8 | polymer | 242 | 27655.8 | 1 | UniProt (G1STW0) Pfam (PF01248) | Oryctolagus cuniculus (rabbit) | |
| 8 | H (H) | 60S ribosomal protein L9 | polymer | 192 | 21871.4 | 1 | UniProt (G1SWI6) Pfam (PF00347) | Oryctolagus cuniculus (rabbit) | |
| 9 | I (I) | 60S ribosomal protein L10 | polymer | 214 | 24643.1 | 1 | UniProt (B7NZQ2) Pfam (PF00252) | Oryctolagus cuniculus (rabbit) | Ribosomal protein L10 (Predicted) |
| 10 | J (J) | Ribosomal protein L11 | polymer | 178 | 20288.5 | 1 | UniProt (G1TUB8) Pfam (PF00281) Pfam (PF00673) | Oryctolagus cuniculus (rabbit) | |
| 11 | K (L) | 60S ribosomal protein L13 | polymer | 211 | 24331.7 | 1 | UniProt (G1TPV0) | Oryctolagus cuniculus (rabbit) | |
| 12 | L (M) | Large ribosomal subunit protein eL14 | polymer | 198 | 21950.3 | 1 | UniProt (G1SZ12) Pfam (PF01929) | Oryctolagus cuniculus (rabbit) | 60S ribosomal protein L14 |
| 13 | M (N) | Ribosomal protein L15 | polymer | 204 | 24207.3 | 1 | UniProt (G1T0C1) Pfam (PF00827) | Oryctolagus cuniculus (rabbit) | |
| 14 | N (O) | uL13 | polymer | 198 | 23047.7 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 15 | O (P) | Large ribosomal subunit protein uL22 | polymer | 187 | 21741.6 | 1 | UniProt (A0AAG1VQ99) | Oryctolagus cuniculus (rabbit) | 60S ribosomal protein L17 |
| 16 | P (Q) | eL18 | polymer | 187 | 21568.5 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 17 | Q (R) | eL19 | polymer | 181 | 21744.2 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 18 | R (S) | eL20 | polymer | 176 | 20827.6 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 19 | S (T) | eL21 | polymer | 160 | 18610.0 | 1 | UniProt (G1SHQ2) Pfam (PF01157) | Oryctolagus cuniculus (rabbit) | |
| 20 | T (U) | eL22 | polymer | 99 | 11495.3 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 21 | U (V) | Ribosomal protein L23 | polymer | 140 | 14892.5 | 1 | UniProt (G1T6D1) Pfam (PF00238) | Oryctolagus cuniculus (rabbit) | |
| 22 | V (W) | eL24 | polymer | 157 | 17825.1 | 1 | UniProt (G1SE28) Pfam (PF01246) | Oryctolagus cuniculus (rabbit) | |
| 23 | W (X) | eL23 | polymer | 156 | 17768.2 | 1 | UniProt (G1SE76) Pfam (PF03939) Pfam (PF00276) | Oryctolagus cuniculus (rabbit) | |
| 24 | X (Y) | uL24 | polymer | 145 | 17303.4 | 1 | UniProt (G1SQH0) Pfam (PF16906) Pfam (PF00467) | Oryctolagus cuniculus (rabbit) | |
| 25 | Y (Z) | 60S ribosomal protein L27 | polymer | 136 | 15835.8 | 1 | UniProt (G1TXF6) Pfam (PF00467) Pfam (PF01777) | Oryctolagus cuniculus (rabbit) | |
| 26 | Z (a) | uL15 | polymer | 148 | 16617.5 | 1 | UniProt (G1SNY0) Pfam (PF00828) | Oryctolagus cuniculus (rabbit) | |
| 27 | AA (b) | eL29 | polymer | 226 | 24931.6 | 1 | UniProt (G1SGR6) Pfam (PF01779) | Oryctolagus cuniculus (rabbit) | |
| 28 | BA (c) | eL30 | polymer | 115 | 12807.1 | 1 | UniProt (G1TDL2) Pfam (PF01248) | Oryctolagus cuniculus (rabbit) | |
| 29 | CA (d) | eL31 | polymer | 125 | 14494.9 | 1 | UniProt (G1SHG0) Pfam (PF01198) | Oryctolagus cuniculus (rabbit) | |
| 30 | DA (e) | Ribosomal protein L32 | polymer | 135 | 15898.9 | 1 | UniProt (A0AAA9WVN6) Pfam (PF01655) UniProt (by SIFTS) (G1TUN8) | Oryctolagus cuniculus (rabbit) | |
| 31 | EA (f) | eL33 | polymer | 110 | 12580.8 | 1 | UniProt (G1SF08) Pfam (PF01247) | Oryctolagus cuniculus (rabbit) | |
| 32 | FA (g) | Large ribosomal subunit protein eL34 | polymer | 126 | 14210.1 | 1 | UniProt (A0AAA9WXS4) | Oryctolagus cuniculus (rabbit) | 60S ribosomal protein L34 |
| 33 | GA (h) | eL35 | polymer | 123 | 14566.6 | 1 | UniProt (G1SIT5) Pfam (PF00831) | Oryctolagus cuniculus (rabbit) | |
| 34 | HA (i) | 60S ribosomal protein L36 | polymer | 105 | 12263.8 | 1 | UniProt (G1TTQ5) Pfam (PF01158) | Oryctolagus cuniculus (rabbit) | |
| 35 | IA (j) | Ribosomal protein L37 | polymer | 97 | 11111.0 | 1 | UniProt (U3KPD5) Pfam (PF01907) | Oryctolagus cuniculus (rabbit) | |
| 36 | JA (k) | eL38 | polymer | 69 | 8107.8 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 37 | KA (l) | eL39 | polymer | 51 | 6455.8 | 1 | UniProt (G1TTN1) Pfam (PF00832) | Oryctolagus cuniculus (rabbit) | |
| 38 | LA (m) | eL40 | polymer | 52 | 6199.6 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 39 | MA (n) | eL41 | polymer | 25 | 3473.5 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 40 | NA (o) | Large ribosomal subunit protein eL42 | polymer | 106 | 12477.0 | 1 | UniProt (A0AAA9WX15) Pfam (PF00935) UniProt (by SIFTS) (G1T040) | Oryctolagus cuniculus (rabbit) | 60S ribosomal protein L36a |
| 41 | OA (p) | eL43 | polymer | 92 | 10299.4 | 1 | UniProt (G1SY53) Pfam (PF01780) | Oryctolagus cuniculus (rabbit) | |
| 42 | PA (r) | eL28 | polymer | 137 | 15783.6 | 1 | UniProt (G1U7L1) Pfam (PF01778) | Oryctolagus cuniculus (rabbit) | |
| 43 | QA (s) | 60S acidic ribosomal protein P0 | polymer | 303 | 33270.5 | 1 | UniProt (A0A1U7UFL5) Pfam (PF00466) Pfam (PF17777) Pfam (PF00428) | Oryctolagus cuniculus (rabbit) | |
| 44 | RA (t) | Ribosomal protein L12 | polymer | 195 | 21295.6 | 1 | UniProt (G1SMR7) Pfam (PF03946) Pfam (PF00298) | Oryctolagus cuniculus (rabbit) | |
| 45 | SA (5) | 28S rRNA | polymer | 3594 | 1164731.9 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 46 | TA (7) | 5S rRNA | polymer | 119 | 38385.8 | 1 | GenBank (2844819966) | Oryctolagus cuniculus (rabbit) | |
| 47 | UA (8) | 5.8S rRNA | polymer | 151 | 48545.7 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 48 | VA (K) | Ribosomal protein | polymer | 217 | 24879.4 | 1 | UniProt (G1SKZ8) Pfam (PF00687) | Oryctolagus cuniculus (rabbit) | |
| 49 | WA (2) | 18S rRNA | polymer | 1697 | 547733.1 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 50 | XA (BB) | uS2 | polymer | 217 | 24361.9 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 51 | YA (CC) | 40S ribosomal protein S3a | polymer | 264 | 30002.1 | 1 | UniProt (G1SS70) Pfam (PF01015) | Oryctolagus cuniculus (rabbit) | |
| 52 | ZA (DD) | uS5 | polymer | 221 | 24441.8 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 53 | AB (EE) | Ribosomal protein S3 | polymer | 281 | 31146.6 | 1 | UniProt (G1TNM3) Pfam (PF07650) Pfam (PF00189) | Oryctolagus cuniculus (rabbit) | |
| 54 | BB (FF) | eS4 | polymer | 262 | 29523.7 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 55 | CB (GG) | Ribosomal protein S5 | polymer | 204 | 22913.5 | 1 | UniProt (G1TFM5) Pfam (PF00177) | Oryctolagus cuniculus (rabbit) | |
| 56 | DB (HH) | 40S ribosomal protein S6 | polymer | 249 | 28751.9 | 1 | UniProt (G1TM55) Pfam (PF01092) | Oryctolagus cuniculus (rabbit) | |
| 57 | EB (II) | 40S ribosomal protein S7 | polymer | 194 | 22168.9 | 1 | UniProt (G1SVB0) | Oryctolagus cuniculus (rabbit) | |
| 58 | FB (JJ) | 40S ribosomal protein S8 | polymer | 206 | 24003.0 | 1 | UniProt (G1TJW1) Pfam (PF01201) | Oryctolagus cuniculus (rabbit) | |
| 59 | GB (KK) | Ribosomal protein S9 (Predicted) | polymer | 194 | 22641.6 | 1 | UniProt (B7NZS8) Pfam (PF00163) Pfam (PF01479) | Oryctolagus cuniculus (rabbit) | |
| 60 | HB (LL) | S10_plectin domain-containing protein | polymer | 149 | 17156.9 | 1 | UniProt (G1U0Y5) Pfam (PF03501) | Oryctolagus cuniculus (rabbit) | |
| 61 | IB (MM) | Ribosomal protein S11 | polymer | 158 | 18468.8 | 1 | UniProt (G1TRM4) Pfam (PF16205) Pfam (PF00366) | Oryctolagus cuniculus (rabbit) | |
| 62 | JB (NN) | 40S ribosomal protein S12 | polymer | 132 | 14539.0 | 1 | UniProt (G1SFR8) Pfam (PF01248) | Oryctolagus cuniculus (rabbit) | |
| 63 | KB (OO) | Ribosomal protein S13 | polymer | 151 | 17259.4 | 1 | UniProt (G1SP51) Pfam (PF08069) Pfam (PF00312) | Oryctolagus cuniculus (rabbit) | |
| 64 | LB (PP) | Small ribosomal subunit protein uS11 | polymer | 151 | 16302.8 | 1 | UniProt (G1T1F0) Pfam (PF00411) | Oryctolagus cuniculus (rabbit) | 40S ribosomal protein S14 |
| 65 | MB (QQ) | uS19 | polymer | 145 | 17049.2 | 1 | UniProt (G1U0Q2) Pfam (PF00203) | Oryctolagus cuniculus (rabbit) | |
| 66 | NB (RR) | Ribosomal protein S16 | polymer | 172 | 19213.5 | 1 | UniProt (G1SGX4) Pfam (PF00380) | Oryctolagus cuniculus (rabbit) | |
| 67 | OB (SS) | eS17 | polymer | 135 | 15552.1 | 1 | UniProt (G1TU13) Pfam (PF00833) | Oryctolagus cuniculus (rabbit) | |
| 68 | PB (TT) | uS13 | polymer | 152 | 17759.8 | 1 | UniProt (G1TPG3) Pfam (PF00416) | Oryctolagus cuniculus (rabbit) | |
| 69 | QB (UU) | eS19 | polymer | 145 | 16235.8 | 1 | UniProt (G1TN62) Pfam (PF01090) | Oryctolagus cuniculus (rabbit) | |
| 70 | RB (VV) | uS10 | polymer | 119 | 13398.8 | 1 | UniProt (G1SIZ2) Pfam (PF00338) | Oryctolagus cuniculus (rabbit) | |
| 71 | SB (WW) | eS21 | polymer | 83 | 9124.4 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 72 | TB (XX) | Ribosomal protein S15a | polymer | 130 | 14865.6 | 1 | UniProt (G1TG89) Pfam (PF00410) | Oryctolagus cuniculus (rabbit) | |
| 73 | UB (YY) | Ribosomal protein S23 | polymer | 143 | 15784.5 | 1 | UniProt (G1SZ47) Pfam (PF00164) | Oryctolagus cuniculus (rabbit) | |
| 74 | VB (ZZ) | 40S ribosomal protein S24 | polymer | 134 | 15548.4 | 1 | UniProt (G1T3D8) Pfam (PF01282) | Oryctolagus cuniculus (rabbit) | |
| 75 | WB (aa) | eS25 | polymer | 125 | 13776.2 | 1 | UniProt (G1TDB3) Pfam (PF03297) | Oryctolagus cuniculus (rabbit) | |
| 76 | XB (bb) | eS26 | polymer | 101 | 11645.8 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 77 | YB (cc) | 40S ribosomal protein S27 | polymer | 84 | 9480.2 | 1 | UniProt (G1TZ76) Pfam (PF01667) | Oryctolagus cuniculus (rabbit) | |
| 78 | ZB (dd) | Ribosomal protein S28 | polymer | 69 | 7855.1 | 1 | UniProt (G1TIB4) Pfam (PF01200) | Oryctolagus cuniculus (rabbit) | |
| 79 | AC (ee) | eS29 | polymer | 56 | 6690.8 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 80 | BC (ff) | 40S ribosomal protein S30 | polymer | 133 | 14498.9 | 1 | UniProt (G1T8A2) Pfam (PF00240) Pfam (PF04758) | Oryctolagus cuniculus (rabbit) | |
| 81 | CC (gg) | Ribosomal protein S27a | polymer | 156 | 18004.0 | 1 | UniProt (G1SK22) Pfam (PF00240) Pfam (PF01599) | Oryctolagus cuniculus (rabbit) | |
| 82 | DC (hh) | RACK1 | polymer | 317 | 35115.7 | 1 | UniProt (G1SJB4) Pfam (PF00400) | Oryctolagus cuniculus (rabbit) | |
| 83 | EC (3) | P-site tRNA | polymer | 87 | 28094.6 | 1 | GenBank (1370526512) | Escherichia coli | |
| 84 | FC (9) | Elongation factor 2 | polymer | 856 | 95232.9 | 1 | UniProt (P13639) Pfam (PF00009) Pfam (PF03144) Pfam (PF14492) Pfam (PF03764) Pfam (PF00679) | Homo sapiens (human) | EF-2 |
| 85 | GC (4) | CrPV IRES | polymer | 190 | 60789.8 | 1 | GenBank (8895506) | Cricket paralysis virus | |
| 86 | HC, KC, LC, MC (p, 2, bb, gg) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 87 | IC, JC (5) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) |
Sequence modifications
D: 2 - 297 (UniProt: P19949)
L: 1 - 211 (UniProt: G1TPV0)
M: 1 - 198 (UniProt: G1SZ12)
s: 1 - 303 (UniProt: A0A1U7UFL5)
JJ: 2 - 207 (UniProt: G1TJW1)
4: 6030 - 6216 (GenBank: 8895506)
| PDB | External Database | Details |
|---|---|---|
| Lys 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ile 46 | - | insertion |
| Ala 47 | - | insertion |
| Pro 48 | - | insertion |
| Arg 49 | - | insertion |
| Pro 50 | - | insertion |
| Ala 51 | - | insertion |
| Ala 52 | - | insertion |
| Gly 53 | - | insertion |
| Pro 54 | - | insertion |
| PDB | External Database | Details |
|---|---|---|
| - | Lys 170 | deletion |
| - | Ala 171 | deletion |
| - | Ala 172 | deletion |
| - | Ala 173 | deletion |
| - | Gln 174 | deletion |
| - | Lys 175 | deletion |
| - | Ala 176 | deletion |
| - | Pro 177 | deletion |
| - | Ala 178 | deletion |
| - | Gln 179 | deletion |
| - | Lys 180 | deletion |
| - | Ala 181 | deletion |
| - | Pro 182 | deletion |
| - | Ala 183 | deletion |
| - | Gln 184 | deletion |
| - | Lys 185 | deletion |
| - | Ala 186 | deletion |
| - | Ala 187 | deletion |
| - | Gly 188 | deletion |
| - | Gln 189 | deletion |
| PDB | External Database | Details |
|---|---|---|
| Leu 262 | Ala 262 | conflict |
| - | Glu 263 | deletion |
| Thr 266 | Ala 267 | conflict |
| Leu 267 | Phe 268 | conflict |
| Ile 269 | Ala 270 | conflict |
| Ile 270 | Asp 271 | conflict |
| - | Ser 273 | deletion |
| - | Ala 274 | deletion |
| - | Phe 275 | deletion |
| - | Val 276 | deletion |
| - | Ala 277 | deletion |
| - | Ala 278 | deletion |
| - | Ala 279 | deletion |
| - | Pro 280 | deletion |
| - | Val 281 | deletion |
| Val 272 | Ala 282 | conflict |
| Arg 273 | Ala 283 | conflict |
| Asp 274 | Ala 284 | conflict |
| Ser 275 | Ala 285 | conflict |
| Thr 276 | Pro 286 | conflict |
| Asp 278 | Ala 288 | conflict |
| Ala 282 | Leu 292 | conflict |
| Gln 284 | Ala 294 | conflict |
| Ser 286 | Ala 296 | conflict |
| Pro 290 | Ala 300 | conflict |
| - | Glu 302 | deletion |
| - | Glu 303 | deletion |
| - | Ser 304 | deletion |
| - | Glu 305 | deletion |
| Asn 294 | Asp 308 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Arg 47 | Gly 47 | conflict |
| PDB | External Database | Details |
|---|---|---|
| C 6217 | - | expression tag |
| U 6218 | - | expression tag |
| U 6219 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 85 |
| Total formula weight | 3493574.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 310.2 | |
| All* | Total formula weight | 3493885.1 |
