6D96

Structure of influenza neuraminidase from strain A/BrevigMission/1/1918(H1N1) expressed in HEK-293E cells

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Neuraminidase	polymer	404	44445.5	8	UniProt (Q9IGQ6) Pfam (PF00064)	Influenza A virus (Influenza A virus (strain A/South Carolina/1/1918 H1N1))
2	I, J, L, N, O (I, J, L, N, O)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	5	In PDB GlyTouCan (G21290RB)
3	K, M (K, M)	alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		367.3	2	In PDB GlyTouCan (G86851RC)
4	AA, AB, BA, FA, GA... (C, H, D, E, A...)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	17	Chemie (NAG)
5	BB, CA, CB, DA, HA... (H, C, D, E, A...)	CALCIUM ION	non-polymer		40.1	18	Chemie (CA)
6	DB, EA, JA, OA, U... (H, C, D, E, A...)	GLYCEROL	non-polymer		92.1	6	Chemie (GOL)
7	EB, FB, GB, HB, IB... (A, B, C, D, E...)	water	water		18.0	1345	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H: 82 - 470 (UniProt: Q9IGQ6)

PDB	External Database	Details
His 66	-	expression tag
His 67	-	expression tag
His 68	-	expression tag
His 69	-	expression tag
His 70	-	expression tag
His 71	-	expression tag
Ser 72	-	expression tag
Leu 73	-	expression tag
Val 74	-	expression tag
Pro 75	-	expression tag
Arg 76	-	expression tag
Gly 77	-	expression tag
Ser 78	-	expression tag
Pro 79	-	expression tag
Ser 80	-	expression tag
Arg 81	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	355563.6
Branched	Number of molecules	7
	Total formula weight	3587.4
Non-Polymers*	Number of molecules	41
	Total formula weight	5034.5
All*	Total formula weight	364185.5

*Water molecules are not included.