6D90
Mammalian 80S ribosome with a double translocated CrPV-IRES, P-site tRNA and eRF1.
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | uL2 | polymer | 257 | 28088.9 | 1 | UniProt (G1TT27) Pfam (PF00181) Pfam (PF03947) In PDB | Oryctolagus cuniculus (Rabbit) | Ribosomal protein L8 |
2 | B | uL3 | polymer | 403 | 46104.9 | 1 | UniProt (G1TL06) Pfam (PF00297) In PDB | Oryctolagus cuniculus (Rabbit) | |
3 | C | uL4 | polymer | 392 | 44232.2 | 1 | UniProt (G1SVW5) Pfam (PF00573) Pfam (PF14374) In PDB | Oryctolagus cuniculus (Rabbit) | Ribosomal protein L4 |
4 | D | uL18 | polymer | 297 | 34479.8 | 1 | UniProt (G1SYJ6) UniProt (by SIFTS) (P19949) In PDB | Oryctolagus cuniculus (Rabbit) | 60S ribosomal protein L5 |
5 | E | eL6 | polymer | 291 | 33028.3 | 1 | UniProt (G1SKF7) Pfam (PF03868) Pfam (PF01159) In PDB | Oryctolagus cuniculus (Rabbit) | 60S ribosomal protein L6 |
6 | F | uL30 | polymer | 249 | 29514.3 | 1 | UniProt (G1SV32) Pfam (PF08079) Pfam (PF00327) In PDB | Oryctolagus cuniculus (Rabbit) | |
7 | G | eL8 | polymer | 242 | 27655.8 | 1 | UniProt (G1STW0) Pfam (PF01248) In PDB | Oryctolagus cuniculus (Rabbit) | |
8 | H | uL6 | polymer | 192 | 21871.4 | 1 | UniProt (G1TX33) Pfam (PF00347) UniProt (by SIFTS) (G1SWI6) In PDB | Oryctolagus cuniculus (Rabbit) | |
9 | I | uL16 | polymer | 214 | 24643.1 | 1 | UniProt (B7NZQ2) Pfam (PF00252) In PDB | Oryctolagus cuniculus (Rabbit) | 60S ribosomal protein L10, Ribosomal protein L10 (Predicted) |
10 | J | uL11 | polymer | 178 | 20288.5 | 1 | UniProt (G1TUB8) Pfam (PF00281) Pfam (PF00673) In PDB | Oryctolagus cuniculus (Rabbit) | Ribosomal protein L11 |
11 | L | eL13 | polymer | 211 | 24331.7 | 1 | Oryctolagus cuniculus (Rabbit) | 60S ribosomal protein L13 | |
12 | M | eL14 | polymer | 198 | 21950.3 | 1 | UniProt (U3KNW6) Pfam (PF01929) UniProt (by SIFTS) (G1SZ12) In PDB | Oryctolagus cuniculus (Rabbit) | Ribosomal protein L14 |
13 | N | eL15 | polymer | 204 | 24207.3 | 1 | UniProt (G1T0C1) Pfam (PF00827) In PDB | Oryctolagus cuniculus (Rabbit) | Ribosomal protein L15 |
14 | O | uL13 | polymer | 199 | 23144.9 | 1 | Oryctolagus cuniculus (Rabbit) | ||
15 | P | uL22 | polymer | 184 | 21444.2 | 1 | UniProt (G1TVT6) Pfam (PF00237) UniProt (by SIFTS) (G1SCJ6) In PDB | Oryctolagus cuniculus (Rabbit) | |
16 | Q | rL18 | polymer | 188 | 21706.6 | 1 | UniProt (G1TX70) Pfam (PF17135) In PDB | Oryctolagus cuniculus (Rabbit) | |
17 | R | eL19 | polymer | 181 | 21744.2 | 1 | UniProt (G1TJR3) Pfam (PF01280) In PDB | Oryctolagus cuniculus (Rabbit) | Ribosomal protein L19 |
18 | S | eL20 | polymer | 176 | 20827.6 | 1 | UniProt (G1TTY7) Pfam (PF01775) In PDB | Oryctolagus cuniculus (Rabbit) | |
19 | T | eL21 | polymer | 160 | 18610.0 | 1 | UniProt (G1SHQ2) Pfam (PF01157) In PDB | Oryctolagus cuniculus (Rabbit) | |
20 | U | eL22 | polymer | 128 | 14799.0 | 1 | UniProt (G1TSG1) Pfam (PF01776) In PDB | Oryctolagus cuniculus (Rabbit) | |
21 | V | uL14 | polymer | 140 | 14892.5 | 1 | UniProt (G1T6D1) Pfam (PF00238) In PDB | Oryctolagus cuniculus (Rabbit) | Ribosomal protein L23 |
22 | W | eL24 | polymer | 157 | 17825.1 | 1 | UniProt (G1SE28) Pfam (PF01246) In PDB | Oryctolagus cuniculus (Rabbit) | |
23 | X | eL23 | polymer | 156 | 17768.2 | 1 | UniProt (G1SE76) Pfam (PF03939) Pfam (PF00276) In PDB | Oryctolagus cuniculus (Rabbit) | |
24 | Y | uL24 | polymer | 145 | 17303.4 | 1 | UniProt (G1SQH0) Pfam (PF16906) Pfam (PF00467) In PDB | Oryctolagus cuniculus (Rabbit) | |
25 | Z | eL27 | polymer | 136 | 15835.8 | 1 | UniProt (G1TXF6) Pfam (PF00467) Pfam (PF01777) In PDB | Oryctolagus cuniculus (Rabbit) | 60S ribosomal protein L27 |
26 | a | uL15 | polymer | 148 | 16617.5 | 1 | UniProt (G1SNY0) Pfam (PF00828) In PDB | Oryctolagus cuniculus (Rabbit) | |
27 | b | eL29 | polymer | 226 | 24931.6 | 1 | UniProt (G1SGR6) Pfam (PF01779) In PDB | Oryctolagus cuniculus (Rabbit) | |
28 | c | eL30 | polymer | 115 | 12807.1 | 1 | UniProt (G1TDL2) Pfam (PF01248) In PDB | Oryctolagus cuniculus (Rabbit) | |
29 | d | eL31 | polymer | 125 | 14494.9 | 1 | UniProt (G1SHG0) Pfam (PF01198) In PDB | Oryctolagus cuniculus (Rabbit) | |
30 | e | eL32 | polymer | 135 | 15898.9 | 1 | UniProt (G1U437) UniProt (by SIFTS) (G1TUN8) Pfam (PF01655) In PDB | Oryctolagus cuniculus (Rabbit) | |
31 | f | eL33 | polymer | 110 | 12580.8 | 1 | UniProt (G1SF08) Pfam (PF01247) In PDB | Oryctolagus cuniculus (Rabbit) | |
32 | g | eL34 | polymer | 126 | 14210.1 | 1 | UniProt (G1U945) UniProt (by SIFTS) (G1TXG5) Pfam (PF01199) In PDB | Oryctolagus cuniculus (Rabbit) | |
33 | h | eL35 | polymer | 123 | 14566.6 | 1 | UniProt (G1SIT5) Pfam (PF00831) In PDB | Oryctolagus cuniculus (Rabbit) | |
34 | i | eL36 | polymer | 105 | 12263.8 | 1 | UniProt (G1TTQ5) Pfam (PF01158) In PDB | Oryctolagus cuniculus (Rabbit) | 60S ribosomal protein L36 |
35 | j | eL37 | polymer | 97 | 11111.0 | 1 | UniProt (U3KPD5) Pfam (PF01907) In PDB | Oryctolagus cuniculus (Rabbit) | Ribosomal protein L37 |
36 | k | eL38 | polymer | 70 | 8238.9 | 1 | UniProt (G1U3J0) UniProt (by SIFTS) (G1U001) Pfam (PF01781) In PDB | Oryctolagus cuniculus (Rabbit) | |
37 | l | eL39 | polymer | 51 | 6455.8 | 1 | UniProt (G1TTN1) Pfam (PF00832) In PDB | Oryctolagus cuniculus (Rabbit) | |
38 | m | eL40 | polymer | 52 | 6199.6 | 1 | Oryctolagus cuniculus (Rabbit) | Ubiquitin-60S ribosomal protein L40, Ubiquitin A-52 residue ribosomal protein fusion product 1 | |
39 | n | eL41 | polymer | 25 | 3473.5 | 1 | Oryctolagus cuniculus (Rabbit) | ||
40 | o | eL42 | polymer | 106 | 12477.0 | 1 | UniProt (G1U344) UniProt (by SIFTS) (G1T040) Pfam (PF00935) In PDB | Oryctolagus cuniculus (Rabbit) | |
41 | p | eL43 | polymer | 92 | 10299.4 | 1 | UniProt (G1SY53) Pfam (PF01780) In PDB | Oryctolagus cuniculus (Rabbit) | |
42 | r | eL28 | polymer | 137 | 15783.6 | 1 | UniProt (G1U7L1) Pfam (PF01778) In PDB | Oryctolagus cuniculus (Rabbit) | |
43 | s | uL10 | polymer | 303 | 33270.5 | 1 | UniProt (G1U6N2) In PDB | Oryctolagus cuniculus (Rabbit) | 60S acidic ribosomal protein P0 |
44 | t | uL11 | polymer | 195 | 21295.6 | 1 | UniProt (G1SMR7) Pfam (PF00298) Pfam (PF03946) In PDB | Oryctolagus cuniculus (Rabbit) | Ribosomal protein L12 |
45 | 5 | 28S rRNA | polymer | 3594 | 1164731.9 | 1 | Oryctolagus cuniculus (Rabbit) | ||
46 | 7 | 5S rRNA | polymer | 119 | 38385.8 | 1 | REF (1304938343) | Oryctolagus cuniculus (Rabbit) | |
47 | 8 | 5.8S rRNA | polymer | 151 | 48545.7 | 1 | Oryctolagus cuniculus (Rabbit) | ||
48 | K | uL1 | polymer | 217 | 24879.4 | 1 | UniProt (G1SKZ8) Pfam (PF00687) In PDB | Oryctolagus cuniculus (Rabbit) | Ribosomal protein |
49 | 2 | 18S rRNA | polymer | 1697 | 547733.1 | 1 | Oryctolagus cuniculus (Rabbit) | ||
50 | 3 | P-tRNA | polymer | 87 | 28094.6 | 1 | GenBank (1370526504) | Escherichia coli | |
51 | BB | uS2 | polymer | 295 | 33080.2 | 1 | UniProt (G1TWL4) UniProt (by SIFTS) (G1TLT8) Pfam (PF00318) Pfam (PF16122) In PDB | Oryctolagus cuniculus (Rabbit) | 40S ribosomal protein SA,37 kDa laminin receptor precursor,37LRP,37/67 kDa laminin receptor,LRP/LR,67 kDa laminin receptor,67LR,Laminin receptor 1,LamR,Laminin-binding protein precursor p40,LBP/p40 |
52 | CC | eS1 | polymer | 264 | 30002.1 | 1 | UniProt (G1SS70) Pfam (PF01015) In PDB | Oryctolagus cuniculus (Rabbit) | 40S ribosomal protein S3a |
53 | DD | uS5 | polymer | 255 | 27518.2 | 1 | UniProt (G1SWM1) Pfam (PF00333) Pfam (PF03719) In PDB | Oryctolagus cuniculus (Rabbit) | |
54 | EE | uS3 | polymer | 281 | 31146.6 | 1 | UniProt (G1TNM3) Pfam (PF07650) Pfam (PF00189) In PDB | Oryctolagus cuniculus (Rabbit) | Ribosomal protein S3 |
55 | FF | eS4 | polymer | 263 | 29654.9 | 1 | UniProt (G1TK17) Pfam (PF08071) Pfam (PF00900) Pfam (PF00467) Pfam (PF16121) In PDB | Oryctolagus cuniculus (Rabbit) | 40S ribosomal protein S4 |
56 | GG | uS7 | polymer | 204 | 22913.5 | 1 | UniProt (G1TFM5) Pfam (PF00177) In PDB | Oryctolagus cuniculus (Rabbit) | Ribosomal protein S5 |
57 | HH | eS6 | polymer | 249 | 28751.9 | 1 | UniProt (G1TM55) Pfam (PF01092) In PDB | Oryctolagus cuniculus (Rabbit) | 40S ribosomal protein S6 |
58 | II | eS7 | polymer | 194 | 22168.9 | 1 | UniProt (G1SVB0) In PDB | Oryctolagus cuniculus (Rabbit) | 40S ribosomal protein S7 |
59 | JJ | eS8 | polymer | 208 | 24263.4 | 1 | UniProt (G1TJW1) Pfam (PF01201) In PDB | Oryctolagus cuniculus (Rabbit) | 40S ribosomal protein S8 |
60 | KK | uS4 | polymer | 194 | 22641.6 | 1 | UniProt (B7NZS8) Pfam (PF00163) Pfam (PF01479) In PDB | Oryctolagus cuniculus (Rabbit) | Ribosomal protein S9 (Predicted) |
61 | LL | eS10 | polymer | 149 | 17156.9 | 1 | UniProt (G1TPV3) Pfam (PF03501) In PDB | Oryctolagus cuniculus (Rabbit) | |
62 | MM | uS17 | polymer | 158 | 18468.8 | 1 | UniProt (G1TRM4) Pfam (PF16205) Pfam (PF00366) In PDB | Oryctolagus cuniculus (Rabbit) | Ribosomal protein S11 |
63 | NN | eS12 | polymer | 132 | 14539.0 | 1 | UniProt (G1SFR8) Pfam (PF01248) In PDB | Oryctolagus cuniculus (Rabbit) | 40S ribosomal protein S12 |
64 | OO | uS15 | polymer | 151 | 17259.4 | 1 | UniProt (G1SP51) Pfam (PF08069) Pfam (PF00312) In PDB | Oryctolagus cuniculus (Rabbit) | Ribosomal protein S13 |
65 | PP | uS11 | polymer | 151 | 16302.8 | 1 | UniProt (G1U472) Pfam (PF00411) UniProt (by SIFTS) (G1T1F0) In PDB | Oryctolagus cuniculus (Rabbit) | |
66 | uS19 | polymer | 145 | 17049.2 | 1 | UniProt (G1U0Q2) Pfam (PF00203) In PDB | Oryctolagus cuniculus (Rabbit) | ||
67 | RR | uS9 | polymer | 172 | 19213.5 | 1 | UniProt (G1SGX4) Pfam (PF00380) In PDB | Oryctolagus cuniculus (Rabbit) | Ribosomal protein S16 |
68 | SS | eS17 | polymer | 135 | 15552.1 | 1 | UniProt (G1TU13) Pfam (PF00833) In PDB | Oryctolagus cuniculus (Rabbit) | |
69 | TT | uS13 | polymer | 152 | 17759.8 | 1 | UniProt (G1TPG3) Pfam (PF00416) In PDB | Oryctolagus cuniculus (Rabbit) | |
70 | UU | eS19 | polymer | 145 | 16235.8 | 1 | UniProt (G1TN62) Pfam (PF01090) In PDB | Oryctolagus cuniculus (Rabbit) | |
71 | VV | uS10 | polymer | 119 | 13398.8 | 1 | UniProt (G1SIZ2) Pfam (PF00338) In PDB | Oryctolagus cuniculus (Rabbit) | |
72 | WW | eS21 | polymer | 83 | 9124.4 | 1 | UniProt (G1TM82) Pfam (PF01249) In PDB | Oryctolagus cuniculus (Rabbit) | 40S ribosomal protein S21 |
73 | XX | uS8 | polymer | 130 | 14865.6 | 1 | UniProt (G1TG89) Pfam (PF00410) In PDB | Oryctolagus cuniculus (Rabbit) | Ribosomal protein S15a |
74 | YY | uS12 | polymer | 143 | 15784.5 | 1 | UniProt (G1SZ47) Pfam (PF00164) In PDB | Oryctolagus cuniculus (Rabbit) | Ribosomal protein S23 |
75 | ZZ | eS24 | polymer | 134 | 15548.4 | 1 | UniProt (G1T3D8) Pfam (PF01282) In PDB | Oryctolagus cuniculus (Rabbit) | 40S ribosomal protein S24 |
76 | aa | eS25 | polymer | 125 | 13776.2 | 1 | UniProt (G1TDB3) Pfam (PF03297) In PDB | Oryctolagus cuniculus (Rabbit) | |
77 | bb | eS26 | polymer | 115 | 12987.5 | 1 | UniProt (G1TFE8) Pfam (PF01283) In PDB | Oryctolagus cuniculus (Rabbit) | 40S ribosomal protein S26 |
78 | cc | eS27 | polymer | 84 | 9480.2 | 1 | UniProt (G1TZ76) Pfam (PF01667) In PDB | Oryctolagus cuniculus (Rabbit) | 40S ribosomal protein S27 |
79 | dd | eS28 | polymer | 69 | 7855.1 | 1 | UniProt (G1TIB4) Pfam (PF01200) In PDB | Oryctolagus cuniculus (Rabbit) | Ribosomal protein S28 |
80 | ee | eS29 | polymer | 56 | 6690.8 | 1 | UniProt (G1U7M4) Pfam (PF00253) In PDB | Oryctolagus cuniculus (Rabbit) | |
81 | ff | eS30 | polymer | 133 | 14498.9 | 1 | UniProt (G1T8A2) Pfam (PF00240) Pfam (PF04758) In PDB | Oryctolagus cuniculus (Rabbit) | 40S ribosomal protein S30 |
82 | gg | eS31 | polymer | 156 | 18004.0 | 1 | UniProt (G1SK22) Pfam (PF00240) Pfam (PF01599) In PDB | Oryctolagus cuniculus (Rabbit) | Ribosomal protein S27a |
83 | hh | RACK1 | polymer | 317 | 35115.7 | 1 | UniProt (G1SJB4) Pfam (PF00400) In PDB | Oryctolagus cuniculus (Rabbit) | |
84 | jj | eRF1 | polymer | 437 | 49120.8 | 1 | UniProt (P62495) Pfam (PF03463) Pfam (PF03464) Pfam (PF03465) In PDB | Homo sapiens (Human) | eRF1,Protein Cl1,TB3-1 |
85 | 4 | CrPV-IRES | polymer | 194 | 62075.5 | 1 | Cricket paralysis virus |
Sequence modifications
Q: 1 - 188 (UniProt: G1TX70)
R: 1 - 181 (UniProt: G1TJR3)
S: 1 - 175 (UniProt: G1TTY7)
U: 1 - 128 (UniProt: G1TSG1)
k: 1 - 70 (UniProt: G1U3J0)
BB: 1 - 295 (UniProt: G1TWL4)
DD: 39 - 293 (UniProt: G1SWM1)
FF: 1 - 263 (UniProt: G1TK17)
JJ: 1 - 208 (UniProt: G1TJW1)
WW: 1 - 83 (UniProt: G1TM82)
bb: 1 - 115 (UniProt: G1TFE8)
jj: 1 - 437 (UniProt: P62495)
PDB | External Database | Details |
---|---|---|
Arg 6 | Leu 6 | conflict |
Arg 14 | Trp 14 | conflict |
Ile 23 | Met 23 | conflict |
Tyr 24 | Cys 24 | conflict |
Arg 38 | His 38 | conflict |
Asn 57 | Lys 57 | conflict |
Met 66 | Val 66 | conflict |
Gly 74 | Asp 74 | conflict |
Arg 75 | Pro 75 | conflict |
Val 86 | Ile 86 | conflict |
Arg 110 | His 110 | conflict |
Gly 117 | Glu 117 | conflict |
Asp 124 | His 124 | conflict |
Arg 150 | Gln 150 | conflict |
Arg 172 | Gly 172 | conflict |
Arg 184 | Trp 184 | conflict |
PDB | External Database | Details |
---|---|---|
Arg 38 | Cys 38 | conflict |
Arg 64 | Gln 64 | conflict |
Thr 94 | Lys 94 | conflict |
PDB | External Database | Details |
---|---|---|
Met 1 | Thr 1 | conflict |
Pro 18 | - | insertion |
Thr 19 | - | insertion |
Pro 20 | Ser 18 | conflict |
Cys 22 | Ser 20 | conflict |
Arg 23 | Pro 21 | conflict |
Thr 24 | Ala 22 | conflict |
Ser 49 | Leu 47 | conflict |
Gln 50 | Glu 48 | conflict |
Arg 95 | His 93 | conflict |
Thr 101 | Ile 99 | conflict |
Thr 102 | Met 100 | conflict |
Gly 104 | Ser 102 | conflict |
Ile 126 | Val 124 | conflict |
Ile 132 | Met 130 | conflict |
Ser 135 | Ala 133 | conflict |
Lys 136 | Arg 134 | conflict |
Arg 138 | Pro 136 | conflict |
Lys 149 | Arg 147 | conflict |
Lys 151 | Arg 149 | conflict |
Thr 168 | Tyr 166 | conflict |
Thr 169 | Ala 167 | conflict |
Phe 176 | - | insertion |
PDB | External Database | Details |
---|---|---|
Leu 18 | Val 18 | conflict |
Gly 32 | Arg 32 | conflict |
Ala 36 | Glu 36 | conflict |
Phe 39 | Ser 39 | conflict |
Gly 54 | Arg 54 | conflict |
Val 60 | Ala 60 | conflict |
Ser 62 | Thr 62 | conflict |
Leu 63 | Ile 63 | conflict |
Arg 97 | His 97 | conflict |
Thr 106 | Ser 106 | conflict |
PDB | External Database | Details |
---|---|---|
Arg 3 | Gln 3 | conflict |
Cys 38 | Tyr 38 | conflict |
Thr 48 | Met 48 | conflict |
Val 66 | Met 66 | conflict |
PDB | External Database | Details |
---|---|---|
Thr 114 | Ala 114 | conflict |
Arg 128 | Gln 128 | conflict |
Thr 135 | Met 135 | conflict |
Arg 155 | His 155 | conflict |
Pro 162 | Leu 162 | conflict |
Arg 180 | Gln 180 | conflict |
PDB | External Database | Details |
---|---|---|
Phe 97 | Cys 59 | conflict |
Ser 101 | Ala 63 | conflict |
Val 141 | Leu 103 | conflict |
Pro 181 | Leu 143 | conflict |
Val 191 | - | insertion |
Met 215 | Leu 176 | conflict |
Asp 271 | Asn 232 | conflict |
Val 274 | Met 235 | conflict |
PDB | External Database | Details |
---|---|---|
Gly 25 | Ser 25 | conflict |
Arg 51 | Lys 51 | conflict |
Thr 78 | Ala 78 | conflict |
Val 156 | Met 156 | conflict |
PDB | External Database | Details |
---|---|---|
Arg 47 | Gly 47 | conflict |
PDB | External Database | Details |
---|---|---|
Asn 3 | Ser 3 | conflict |
Asp 4 | Asn 4 | conflict |
Gln 33 | Pro 33 | conflict |
Phe 50 | Ser 50 | conflict |
Ala 75 | Ser 75 | conflict |
Asp 76 | His 76 | conflict |
Lys 81 | Gln 81 | conflict |
PDB | External Database | Details |
---|---|---|
Arg 28 | Cys 28 | conflict |
Ala 56 | Val 56 | conflict |
PDB | External Database | Details |
---|---|---|
Ala 183 | Gly 183 | conflict |
Ala 184 | Gly 184 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 85 |
Total formula weight | 3465649.2 | |
All* | Total formula weight | 3465649.2 |