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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

6D90

Mammalian 80S ribosome with a double translocated CrPV-IRES, P-site tRNA and eRF1.

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)		Ribosomal protein L8polymer25728088.91UniProt (G1TT27)
Pfam (PF00181)
Pfam (PF03947)		Oryctolagus cuniculus (rabbit)
2B
(B)		uL3polymer40346104.91UniProt (G1TL06)
Pfam (PF00297)		Oryctolagus cuniculus (rabbit)
3C
(C)		Ribosomal protein L4polymer39244232.21UniProt (G1SVW5)
Pfam (PF00573)
Pfam (PF14374)		Oryctolagus cuniculus (rabbit)
4D
(D)		Large ribosomal subunit protein uL18polymer29734479.81UniProt (P19949)Oryctolagus cuniculus (rabbit)60S ribosomal protein L5
5E
(E)		60S ribosomal protein L6polymer29133028.31UniProt (G1SKF7)
Pfam (PF03868)
Pfam (PF01159)		Oryctolagus cuniculus (rabbit)
6F
(F)		uL30polymer24929514.31UniProt (G1SV32)
Pfam (PF08079)
Pfam (PF00327)		Oryctolagus cuniculus (rabbit)
7G
(G)		eL8polymer24227655.81UniProt (G1STW0)
Pfam (PF01248)		Oryctolagus cuniculus (rabbit)
8H
(H)		60S ribosomal protein L9polymer19221871.41UniProt (G1SWI6)
Pfam (PF00347)		Oryctolagus cuniculus (rabbit)
9I
(I)		60S ribosomal protein L10polymer21424643.11UniProt (B7NZQ2)
Pfam (PF00252)		Oryctolagus cuniculus (rabbit)Ribosomal protein L10 (Predicted)
10J
(J)		Ribosomal protein L11polymer17820288.51UniProt (G1TUB8)
Pfam (PF00281)
Pfam (PF00673)		Oryctolagus cuniculus (rabbit)
11K
(L)		eL13polymer21124331.71Oryctolagus cuniculus (Rabbit)
12L
(M)		Large ribosomal subunit protein eL14polymer19821950.31UniProt (G1SZ12)
Pfam (PF01929)		Oryctolagus cuniculus (rabbit)60S ribosomal protein L14
13M
(N)		Ribosomal protein L15polymer20424207.31UniProt (G1T0C1)
Pfam (PF00827)		Oryctolagus cuniculus (rabbit)
14N
(O)		uL13polymer19923144.91Oryctolagus cuniculus (Rabbit)
15O
(P)		Large ribosomal subunit protein uL22polymer18421444.21UniProt (G1SCJ6)
Pfam (PF00237)		Oryctolagus cuniculus (rabbit)60S ribosomal protein L17
16P
(Q)		rL18polymer18821706.61UniProt (G1TX70)
Pfam (PF17135)		Oryctolagus cuniculus (rabbit)
17Q
(R)		Ribosomal protein L19polymer18121744.21UniProt (G1TJR3)
Pfam (PF01280)		Oryctolagus cuniculus (rabbit)
18R
(S)		60S ribosomal protein L18apolymer17620827.61UniProt (G1TTY7)
Pfam (PF01775)		Oryctolagus cuniculus (rabbit)
19S
(T)		eL21polymer16018610.01UniProt (G1SHQ2)
Pfam (PF01157)		Oryctolagus cuniculus (rabbit)
20T
(U)		eL22polymer12814799.01UniProt (G1TSG1)
Pfam (PF01776)		Oryctolagus cuniculus (rabbit)
21U
(V)		Ribosomal protein L23polymer14014892.51UniProt (G1T6D1)
Pfam (PF00238)		Oryctolagus cuniculus (rabbit)
22V
(W)		eL24polymer15717825.11UniProt (G1SE28)
Pfam (PF01246)		Oryctolagus cuniculus (rabbit)
23W
(X)		eL23polymer15617768.21UniProt (G1SE76)
Pfam (PF03939)
Pfam (PF00276)		Oryctolagus cuniculus (rabbit)
24X
(Y)		uL24polymer14517303.41UniProt (G1SQH0)
Pfam (PF16906)
Pfam (PF00467)		Oryctolagus cuniculus (rabbit)
25Y
(Z)		60S ribosomal protein L27polymer13615835.81UniProt (G1TXF6)
Pfam (PF00467)
Pfam (PF01777)		Oryctolagus cuniculus (rabbit)
26Z
(a)		uL15polymer14816617.51UniProt (G1SNY0)
Pfam (PF00828)		Oryctolagus cuniculus (rabbit)
27AA
(b)		eL29polymer22624931.61UniProt (G1SGR6)
Pfam (PF01779)		Oryctolagus cuniculus (rabbit)
28BA
(c)		eL30polymer11512807.11UniProt (G1TDL2)
Pfam (PF01248)		Oryctolagus cuniculus (rabbit)
29CA
(d)		eL31polymer12514494.91UniProt (G1SHG0)
Pfam (PF01198)		Oryctolagus cuniculus (rabbit)
30DA
(e)		Ribosomal protein L32polymer13515898.91UniProt (A0AAA9WVN6)
Pfam (PF01655)
UniProt (by SIFTS) (G1TUN8)		Oryctolagus cuniculus (rabbit)
31EA
(f)		eL33polymer11012580.81UniProt (G1SF08)
Pfam (PF01247)		Oryctolagus cuniculus (rabbit)
32FA
(g)		Large ribosomal subunit protein eL34polymer12614210.11UniProt (A0AAA9WXS4)Oryctolagus cuniculus (rabbit)60S ribosomal protein L34
33GA
(h)		eL35polymer12314566.61UniProt (G1SIT5)
Pfam (PF00831)		Oryctolagus cuniculus (rabbit)
34HA
(i)		60S ribosomal protein L36polymer10512263.81UniProt (G1TTQ5)
Pfam (PF01158)		Oryctolagus cuniculus (rabbit)
35IA
(j)		Ribosomal protein L37polymer9711111.01UniProt (U3KPD5)
Pfam (PF01907)		Oryctolagus cuniculus (rabbit)
36JA
(k)		eL38polymer708238.91UniProt (G1U3J0)
Pfam (PF01781)
UniProt (by SIFTS) (G1U001)		Oryctolagus cuniculus (rabbit)
37KA
(l)		eL39polymer516455.81UniProt (G1TTN1)
Pfam (PF00832)		Oryctolagus cuniculus (rabbit)
38LA
(m)		eL40polymer526199.61Oryctolagus cuniculus (Rabbit)
39MA
(n)		eL41polymer253473.51Oryctolagus cuniculus (Rabbit)
40NA
(o)		Large ribosomal subunit protein eL42polymer10612477.01UniProt (A0AAA9WX15)
Pfam (PF00935)
UniProt (by SIFTS) (G1T040)		Oryctolagus cuniculus (rabbit)60S ribosomal protein L36a
41OA
(p)		eL43polymer9210299.41UniProt (G1SY53)
Pfam (PF01780)		Oryctolagus cuniculus (rabbit)
42PA
(r)		eL28polymer13715783.61UniProt (G1U7L1)
Pfam (PF01778)		Oryctolagus cuniculus (rabbit)
43QA
(s)		60S acidic ribosomal protein P0polymer30333270.51UniProt (A0A1U7UFL5)
Pfam (PF00428)
Pfam (PF00466)
Pfam (PF17777)		Oryctolagus cuniculus (rabbit)
44RA
(t)		Ribosomal protein L12polymer19521295.61UniProt (G1SMR7)
Pfam (PF03946)
Pfam (PF00298)		Oryctolagus cuniculus (rabbit)
45SA
(5)		28S rRNApolymer35941164731.91Oryctolagus cuniculus (Rabbit)
46TA
(7)		5S rRNApolymer11938385.81GenBank (2844819966)Oryctolagus cuniculus (rabbit)
47UA
(8)		5.8S rRNApolymer15148545.71Oryctolagus cuniculus (Rabbit)
48VA
(K)		Ribosomal proteinpolymer21724879.41UniProt (G1SKZ8)
Pfam (PF00687)		Oryctolagus cuniculus (rabbit)
49WA
(2)		18S rRNApolymer1697547733.11Oryctolagus cuniculus (Rabbit)
50XA
(3)		P-tRNApolymer8728094.61GenBank (1370526504)Escherichia coli
51YA
(BB)		Small ribosomal subunit protein uS2polymer29533080.21UniProt (G1TLT8)
Pfam (PF00318)
Pfam (PF16122)		Oryctolagus cuniculus (rabbit)37 kDa laminin receptor precursor,37LRP,37/67 kDa laminin receptor,LRP/LR,67 kDa laminin receptor,67LR,Laminin receptor 1,LamR,Laminin-binding protein precursor p40,LBP/p40
52ZA
(CC)		40S ribosomal protein S3apolymer26430002.11UniProt (G1SS70)
Pfam (PF01015)		Oryctolagus cuniculus (rabbit)
53AB
(DD)		uS5polymer25527518.21UniProt (G1SWM1)
Pfam (PF00333)
Pfam (PF03719)		Oryctolagus cuniculus (rabbit)
54BB
(EE)		Ribosomal protein S3polymer28131146.61UniProt (G1TNM3)
Pfam (PF07650)
Pfam (PF00189)		Oryctolagus cuniculus (rabbit)
55CB
(FF)		40S ribosomal protein S4polymer26329654.91UniProt (G1TK17)
Pfam (PF08071)
Pfam (PF00900)
Pfam (PF00467)
Pfam (PF16121)		Oryctolagus cuniculus (rabbit)
56DB
(GG)		Ribosomal protein S5polymer20422913.51UniProt (G1TFM5)
Pfam (PF00177)		Oryctolagus cuniculus (rabbit)
57EB
(HH)		40S ribosomal protein S6polymer24928751.91UniProt (G1TM55)
Pfam (PF01092)		Oryctolagus cuniculus (rabbit)
58FB
(II)		40S ribosomal protein S7polymer19422168.91UniProt (G1SVB0)Oryctolagus cuniculus (rabbit)
59GB
(JJ)		40S ribosomal protein S8polymer20824263.41UniProt (G1TJW1)
Pfam (PF01201)		Oryctolagus cuniculus (rabbit)
60HB
(KK)		Ribosomal protein S9 (Predicted)polymer19422641.61UniProt (B7NZS8)
Pfam (PF00163)
Pfam (PF01479)		Oryctolagus cuniculus (rabbit)
61IB
(LL)		S10_plectin domain-containing proteinpolymer14917156.91UniProt (G1U0Y5)
Pfam (PF03501)		Oryctolagus cuniculus (rabbit)
62JB
(MM)		Ribosomal protein S11polymer15818468.81UniProt (G1TRM4)
Pfam (PF16205)
Pfam (PF00366)		Oryctolagus cuniculus (rabbit)
63KB
(NN)		40S ribosomal protein S12polymer13214539.01UniProt (G1SFR8)
Pfam (PF01248)		Oryctolagus cuniculus (rabbit)
64LB
(OO)		Ribosomal protein S13polymer15117259.41UniProt (G1SP51)
Pfam (PF08069)
Pfam (PF00312)		Oryctolagus cuniculus (rabbit)
65MB
(PP)		Small ribosomal subunit protein uS11polymer15116302.81UniProt (G1T1F0)
Pfam (PF00411)		Oryctolagus cuniculus (rabbit)40S ribosomal protein S14
66NB
(QQ)		uS19polymer14517049.21UniProt (G1U0Q2)
Pfam (PF00203)		Oryctolagus cuniculus (rabbit)
67OB
(RR)		Ribosomal protein S16polymer17219213.51UniProt (G1SGX4)
Pfam (PF00380)		Oryctolagus cuniculus (rabbit)
68PB
(SS)		eS17polymer13515552.11UniProt (G1TU13)
Pfam (PF00833)		Oryctolagus cuniculus (rabbit)
69QB
(TT)		uS13polymer15217759.81UniProt (G1TPG3)
Pfam (PF00416)		Oryctolagus cuniculus (rabbit)
70RB
(UU)		eS19polymer14516235.81UniProt (G1TN62)
Pfam (PF01090)		Oryctolagus cuniculus (rabbit)
71SB
(VV)		uS10polymer11913398.81UniProt (G1SIZ2)
Pfam (PF00338)		Oryctolagus cuniculus (rabbit)
72TB
(WW)		40S ribosomal protein S21polymer839124.41UniProt (G1TM82)
Pfam (PF01249)		Oryctolagus cuniculus (rabbit)
73UB
(XX)		Ribosomal protein S15apolymer13014865.61UniProt (G1TG89)
Pfam (PF00410)		Oryctolagus cuniculus (rabbit)
74VB
(YY)		Ribosomal protein S23polymer14315784.51UniProt (G1SZ47)
Pfam (PF00164)		Oryctolagus cuniculus (rabbit)
75WB
(ZZ)		40S ribosomal protein S24polymer13415548.41UniProt (G1T3D8)
Pfam (PF01282)		Oryctolagus cuniculus (rabbit)
76XB
(aa)		eS25polymer12513776.21UniProt (G1TDB3)
Pfam (PF03297)		Oryctolagus cuniculus (rabbit)
77YB
(bb)		40S ribosomal protein S26polymer11512987.51UniProt (G1TFE8)
Pfam (PF01283)		Oryctolagus cuniculus (rabbit)
78ZB
(cc)		40S ribosomal protein S27polymer849480.21UniProt (G1TZ76)
Pfam (PF01667)		Oryctolagus cuniculus (rabbit)
79AC
(dd)		Ribosomal protein S28polymer697855.11UniProt (G1TIB4)
Pfam (PF01200)		Oryctolagus cuniculus (rabbit)
80BC
(ee)		eS29polymer566690.81UniProt (G1U7M4)
Pfam (PF00253)		Oryctolagus cuniculus (rabbit)
81CC
(ff)		40S ribosomal protein S30polymer13314498.91UniProt (G1T8A2)
Pfam (PF00240)
Pfam (PF04758)		Oryctolagus cuniculus (rabbit)
82DC
(gg)		Ribosomal protein S27apolymer15618004.01UniProt (G1SK22)
Pfam (PF00240)
Pfam (PF01599)		Oryctolagus cuniculus (rabbit)
83EC
(hh)		RACK1polymer31735115.71UniProt (G1SJB4)
Pfam (PF00400)		Oryctolagus cuniculus (rabbit)
84FC
(jj)		Eukaryotic peptide chain release factor subunit 1polymer43749120.81UniProt (P62495)
Pfam (PF03463)
Pfam (PF03464)
Pfam (PF03465)		Homo sapiens (human)eRF1,Protein Cl1,TB3-1
85GC
(4)		CrPV-IRESpolymer19462075.51GenBank (KP974707.1)Cricket paralysis virus
Sequence modifications
D: 2 - 297 (UniProt: P19949)
PDBExternal DatabaseDetails
Lys 1-expression tag
M: 1 - 198 (UniProt: G1SZ12)
PDBExternal DatabaseDetails
-Lys 170deletion
-Ala 171deletion
-Ala 172deletion
-Ala 173deletion
-Gln 174deletion
-Lys 175deletion
-Ala 176deletion
-Pro 177deletion
-Ala 178deletion
-Gln 179deletion
-Lys 180deletion
-Ala 181deletion
-Pro 182deletion
-Ala 183deletion
-Gln 184deletion
-Lys 185deletion
-Ala 186deletion
-Ala 187deletion
-Gly 188deletion
-Gln 189deletion
Q: 1 - 188 (UniProt: G1TX70)
PDBExternal DatabaseDetails
Arg 6Leu 6conflict
Arg 14Trp 14conflict
Ile 23Met 23conflict
Tyr 24Cys 24conflict
Arg 38His 38conflict
Asn 57Lys 57conflict
Met 66Val 66conflict
Gly 74Asp 74conflict
Arg 75Pro 75conflict
Val 86Ile 86conflict
Arg 110His 110conflict
Gly 117Glu 117conflict
Asp 124His 124conflict
Arg 150Gln 150conflict
Arg 172Gly 172conflict
Arg 184Trp 184conflict
R: 1 - 181 (UniProt: G1TJR3)
PDBExternal DatabaseDetails
Arg 38Cys 38conflict
Arg 64Gln 64conflict
Thr 94Lys 94conflict
S: 1 - 175 (UniProt: G1TTY7)
PDBExternal DatabaseDetails
Met 1Thr 1conflict
Pro 18-insertion
Thr 19-insertion
Pro 20Ser 18conflict
Cys 22Ser 20conflict
Arg 23Pro 21conflict
Thr 24Ala 22conflict
Ser 49Leu 47conflict
Gln 50Glu 48conflict
Arg 95His 93conflict
Thr 101Ile 99conflict
Thr 102Met 100conflict
Gly 104Ser 102conflict
Ile 126Val 124conflict
Ile 132Met 130conflict
Ser 135Ala 133conflict
Lys 136Arg 134conflict
Arg 138Pro 136conflict
Lys 149Arg 147conflict
Lys 151Arg 149conflict
Thr 168Tyr 166conflict
Thr 169Ala 167conflict
Phe 176-insertion
U: 1 - 128 (UniProt: G1TSG1)
PDBExternal DatabaseDetails
Leu 18Val 18conflict
Gly 32Arg 32conflict
Ala 36Glu 36conflict
Phe 39Ser 39conflict
Gly 54Arg 54conflict
Val 60Ala 60conflict
Ser 62Thr 62conflict
Leu 63Ile 63conflict
Arg 97His 97conflict
Thr 106Ser 106conflict
k: 1 - 70 (UniProt: G1U3J0)
PDBExternal DatabaseDetails
Arg 3Gln 3conflict
Cys 38Tyr 38conflict
Thr 48Met 48conflict
Val 66Met 66conflict
s: 1 - 303 (UniProt: A0A1U7UFL5)
PDBExternal DatabaseDetails
Leu 262Ala 262conflict
-Glu 263deletion
Thr 266Ala 267conflict
Leu 267Phe 268conflict
Ile 269Ala 270conflict
Ile 270Asp 271conflict
-Ser 273deletion
-Ala 274deletion
-Phe 275deletion
-Val 276deletion
-Ala 277deletion
-Ala 278deletion
-Ala 279deletion
-Pro 280deletion
-Val 281deletion
Val 272Ala 282conflict
Arg 273Ala 283conflict
Asp 274Ala 284conflict
Ser 275Ala 285conflict
Thr 276Pro 286conflict
Asp 278Ala 288conflict
Ala 282Leu 292conflict
Gln 284Ala 294conflict
Ser 286Ala 296conflict
Pro 290Ala 300conflict
-Glu 302deletion
-Glu 303deletion
-Ser 304deletion
-Glu 305deletion
Asn 294Asp 308conflict
BB: 1 - 295 (UniProt: G1TLT8)
PDBExternal DatabaseDetails
Thr 114Ala 114conflict
Glu 235Ala 235conflict
Met 252Val 252conflict
Met 288Val 288conflict
DD: 39 - 293 (UniProt: G1SWM1)
PDBExternal DatabaseDetails
Phe 97Cys 59conflict
Ser 101Ala 63conflict
Val 141Leu 103conflict
Pro 181Leu 143conflict
Val 191-insertion
Met 215Leu 176conflict
Asp 271Asn 232conflict
Val 274Met 235conflict
FF: 1 - 263 (UniProt: G1TK17)
PDBExternal DatabaseDetails
Gly 25Ser 25conflict
Arg 51Lys 51conflict
Thr 78Ala 78conflict
Val 156Met 156conflict
JJ: 1 - 208 (UniProt: G1TJW1)
PDBExternal DatabaseDetails
Arg 47Gly 47conflict
WW: 1 - 83 (UniProt: G1TM82)
PDBExternal DatabaseDetails
Asn 3Ser 3conflict
Asp 4Asn 4conflict
Gln 33Pro 33conflict
Phe 50Ser 50conflict
Ala 75Ser 75conflict
Asp 76His 76conflict
Lys 81Gln 81conflict
bb: 1 - 115 (UniProt: G1TFE8)
PDBExternal DatabaseDetails
Arg 28Cys 28conflict
Ala 56Val 56conflict
jj: 1 - 437 (UniProt: P62495)
PDBExternal DatabaseDetails
Ala 183Gly 183conflict
Ala 184Gly 184conflict
4: 6030 - 6223 (GenBank: KP974707.1)
PDBExternal DatabaseDetails
-G 6217deletion
C 6219A 6220conflict
U 6220C 6221conflict
G 6222U 6223conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains85
Total formula weight3465649.2
All*Total formula weight3465649.2
*Water molecules are not included.

237735

PDB entries from 2025-06-18

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