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6D6V

CryoEM structure of Tetrahymena telomerase with telomeric DNA at 4.8 Angstrom resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Telomerase reverse transcriptasepolymer1117133486.91UniProt (O77448)
Pfam (PF11474)
Pfam (PF12009)
Pfam (PF00078)
Tetrahymena thermophilaTelomerase catalytic subunit,Telomerase subunit P133
2B
(D)
Telomerase-associated protein 82polymer70182040.31UniProt (D2CVN6)
Pfam (PF08646)
Tetrahymena thermophila
3C
(F)
Telomerase holoenzyme TEB heterotrimer Teb3 subunitpolymer12114007.61UniProt (A0A0U8UFF4)
Pfam (PF08661)
Tetrahymena thermophila
4D
(E)
Telomerase holoenzyme Teb2 subunitpolymer26930993.01UniProt (A0A0U8TRG9)Tetrahymena thermophila
5E
(B)
RNA (159-MER)polymer15950747.01GenBank (15148878)Tetrahymena thermophila
6F
(C)
DNA (5'-D(P*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*G)-3')polymer196059.91Tetrahymena thermophila
7G
(G)
Telomerase-associated protein 50polymer15713379.51Tetrahymena thermophila
8H
(H)
Telomerase associated protein p65polymer54264207.41UniProt (Q6JXI6)
Pfam (PF05383)
Pfam (PF00076)
UniProt (by SIFTS) (W7X6T2)
Tetrahymena thermophila
9I
(D)
ZINC IONnon-polymer65.41Chemie (ZN)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight394921.6
Non-Polymers*Number of molecules1
Total formula weight65.4
All*Total formula weight394987.0
*Water molecules are not included.

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PDB entries from 2024-11-06

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