6D4V
M. thermoresistible GuaB2 delta-CBS in complex with inhibitor Compound 22 (VCC061422)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase | polymer | 389 | 39854.5 | 1 | UniProt (G7CNL4) Pfam (PF00478) | Mycobacterium thermoresistibile | IMPDH,IMPDH |
2 | B (A) | INOSINIC ACID | non-polymer | 348.2 | 1 | Chemie (IMP) | |||
3 | C (A) | 2-cyclohexyl-1-{4-[(isoquinolin-5-yl)sulfonyl]piperazin-1-yl}ethan-1-one | non-polymer | 401.5 | 1 | Chemie (FWM) | |||
4 | D (A) | water | water | 18.0 | 218 | Chemie (HOH) |
Sequence modifications
A: 3 - 110 (UniProt: G7CNL4)
A: 113 - 389 (UniProt: G7CNL4)
PDB | External Database | Details |
---|---|---|
Gly 1 | - | expression tag |
Ser 2 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 111 | - | linker |
Gly 112 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 39854.5 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 749.7 | |
All* | Total formula weight | 40604.2 |