6D4T
M. thermoresistible GuaB2 delta-CBS in complex with inhibitor Compound 45 (VCC117054)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase | polymer | 389 | 39854.5 | 1 | UniProt (G7CNL4) Pfam (PF00478) | Mycobacterium thermoresistibile | IMPDH,IMPDH |
| 2 | B (A) | INOSINIC ACID | non-polymer | 348.2 | 1 | Chemie (IMP) | |||
| 3 | C (A) | (2S)-N-(2H-1,3-benzodioxol-5-yl)-4-[(isoquinolin-5-yl)sulfonyl]-2-methylpiperazine-1-carboxamide | non-polymer | 454.5 | 1 | Chemie (FWS) | |||
| 4 | D (A) | water | water | 18.0 | 298 | Chemie (HOH) |
Sequence modifications
A: 3 - 110 (UniProt: G7CNL4)
A: 113 - 389 (UniProt: G7CNL4)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Ser 2 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 111 | - | linker |
| Gly 112 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39854.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 802.7 | |
| All* | Total formula weight | 40657.2 |
