6D4P

Ube2D1 in complex with ubiquitin variant Ubv.D1.1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Ubiquitin-conjugating enzyme E2 D1	polymer	149	16750.1	1	UniProt (P51668) Pfam (PF00179) In PDB	Homo sapiens (Human)	(E3-independent) E2 ubiquitin-conjugating enzyme D1,E2 ubiquitin-conjugating enzyme D1,Stimulator of Fe transport,SFT,UBC4/5 homolog,UbcH5,Ubiquitin carrier protein D1,Ubiquitin-conjugating enzyme E2(17)KB 1,Ubiquitin-conjugating enzyme E2-17 kDa 1,Ubiquitin-protein ligase D1
2	C	Ubiquitin Variant Ubv.D1.1	polymer	88	9984.3	1	UniProt (Q59EM9) Pfam (PF00240) In PDB	Homo sapiens (Human)
3		water	water		18.0	24	Chemie (HOH)

Sequence modifications

A: 1 - 147 (UniProt: P51668)

PDB	External Database	Details
Gly -1	-	expression tag
Ala 0	-	expression tag

C: 1 - 76 (UniProt: Q59EM9)

PDB	External Database	Details
Gly -11	-	expression tag
Ala -10	-	expression tag
Gly -9	-	expression tag
Gly -8	-	expression tag
Asp -7	-	expression tag
Tyr -6	-	expression tag
Lys -5	-	expression tag
Asp -4	-	expression tag
Asp -3	-	expression tag
Asp -2	-	expression tag
Asp -1	-	expression tag
Lys 0	-	expression tag
Lys 7	Thr 23	engineered mutation
Phe 8	Leu 24	engineered mutation
Trp 9	Thr 25	engineered mutation
Lys 64	Glu 80	engineered mutation
Phe 65	Ser 81	engineered mutation
Tyr 68	His 84	engineered mutation
Ala 70	Val 86	engineered mutation
Tyr 71	Leu 87	engineered mutation
Gly 72	Arg 88	engineered mutation
Ala 75	Gly 91	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	26734.4
All*	Total formula weight	26734.4

*Water molecules are not included.