6D28
Crystal Structure of the N-domain of the ER Hsp90 chaperone GRP94 in complex with the specific ligand NECA
Replaces: 1QY5Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Endoplasmin | polymer | 273 | 31055.8 | 1 | UniProt (P41148) Pfam (PF13589) | Canis lupus familiaris (Dog) | 94 kDa glucose-regulated protein,GRP-94,Heat shock protein 90 kDa beta member 1 |
| 2 | B (A) | N-ETHYL-5'-CARBOXAMIDO ADENOSINE | non-polymer | 308.3 | 1 | Chemie (NEC) PubChem (104795) PubChem (23913416) PubChem (24867503) PubChem (40967901) PubChem (40967902) PubChem (44308232) PubChem (44338050) PubChem (686179) PubChem (50987963) PubChem (1254895) PubChem (5342881) PubChem (2868392) PubChem (6541320) PubChem (6603839) PubChem (6604901) PubChem (6610317) PubChem (7068779) PubChem (7256363) PubChem (7256365) PubChem (448222) PubChem (11957539) PubChem (118705485) PubChem (124720172) PubChem (133688337) PubChem (138106599) | |||
| 3 | C (A) | 1-METHOXY-2-(2-METHOXYETHOXY)ETHANE | non-polymer | 134.2 | 1 | Chemie (M2M) PubChem (8150) | |||
| 4 | D (A) | water | water | 18.0 | 221 | Chemie (HOH) |
Sequence modifications
A: 69 - 337 (UniProt: P41148)
| PDB | External Database | Details |
|---|---|---|
| Gly 65 | - | expression tag |
| Ser 66 | - | expression tag |
| His 67 | - | expression tag |
| Met 68 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31055.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 442.5 | |
| All* | Total formula weight | 31498.3 |
