6D28
Crystal Structure of the N-domain of the ER Hsp90 chaperone GRP94 in complex with the specific ligand NECA
Replaces: 1QY5Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Endoplasmin | polymer | 273 | 31055.8 | 1 | UniProt (P41148) Pfam (PF13589) | Canis lupus familiaris (Dog) | 94 kDa glucose-regulated protein,GRP-94,Heat shock protein 90 kDa beta member 1 |
| 2 | B (A) | N-ETHYL-5'-CARBOXAMIDO ADENOSINE | non-polymer | 308.3 | 1 | Chemie (NEC) | |||
| 3 | C (A) | 1-METHOXY-2-(2-METHOXYETHOXY)ETHANE | non-polymer | 134.2 | 1 | Chemie (M2M) | |||
| 4 | D (A) | water | water | 18.0 | 221 | Chemie (HOH) |
Sequence modifications
A: 69 - 337 (UniProt: P41148)
| PDB | External Database | Details |
|---|---|---|
| Gly 65 | - | expression tag |
| Ser 66 | - | expression tag |
| His 67 | - | expression tag |
| Met 68 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31055.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 442.5 | |
| All* | Total formula weight | 31498.3 |
