6D0F
Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with 3OHTPE and GRIP Peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Estrogen receptor | polymer | 250 | 28440.5 | 2 | UniProt (P03372) Pfam (PF00104) | Homo sapiens (Human) | ER,ER-alpha,Estradiol receptor,Nuclear receptor subfamily 3 group A member 1 |
| 2 | C, D (C, D) | GRIP Peptide | polymer | 10 | 1276.5 | 2 | UniProt (by SIFTS) (Q15596) | Homo sapiens | |
| 3 | E, F (A, B) | 4,4',4''-[(2R)-butane-1,1,2-triyl]triphenol | non-polymer | 334.4 | 2 | Chemie (FYS) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 63 | Chemie (HOH) |
Sequence modifications
A, B: 305 - 554 (UniProt: P03372)
| PDB | External Database | Details |
|---|---|---|
| Ser 537 | Tyr 537 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 59434.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 668.8 | |
| All* | Total formula weight | 60102.8 |
