6CZS
Crystal structure of human pro-cathepsin H C26S mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Pro-cathepsin H | polymer | 335 | 37417.5 | 1 | UniProt (P09668) Pfam (PF08246) Pfam (PF00112) | Homo sapiens (Human) | |
| 2 | B (B) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G22768VO) | |||
| 3 | C, D (C, D) | alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose | branched | 342.3 | 2 | In PDB BIRD (PRD_900006) GlyTouCan (G92130SN) | trehalose | ||
| 4 | E (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 5 | F, G, H, I, J (A) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 6 | K, L (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 7 | M (A) | water | water | 18.0 | 498 | Chemie (HOH) |
Sequence modifications
A: 1 - 335 (UniProt: P09668)
| PDB | External Database | Details |
|---|---|---|
| Ser 141 | Cys 141 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37417.5 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1595.4 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 772.4 | |
| All* | Total formula weight | 39785.3 |
