6CZ5
Crystal structure of small molecule AMP-acrylamide covalently bound to DDX3 S228C
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | ATP-dependent RNA helicase DDX3X | polymer | 480 | 54110.3 | 1 | UniProt (O00571) Pfam (PF00270) Pfam (PF00271) In PDB | Homo sapiens (Human) | DEAD box protein 3, X-chromosomal, DEAD box, X isoform, Helicase-like protein 2, HLP2 |
| 2 | A | 5'-O-[(R)-hydroxy(propanoylamino)phosphoryl]adenosine | non-polymer | 402.3 | 1 | Chemie (FPJ) |
Sequence modifications
A: 132 - 607 (UniProt: O00571)
| PDB | External Database | Details |
|---|---|---|
| Gly 128 | - | expression tag |
| Ser 129 | - | expression tag |
| Phe 130 | - | expression tag |
| Thr 131 | - | expression tag |
| Cys 228 | Ser 228 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 54110.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 402.3 | |
| All* | Total formula weight | 54512.6 |
