6CY7
Human Stimulator of Interferon Genes
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Stimulator of interferon genes protein | polymer | 241 | 27137.6 | 1 | UniProt (Q86WV6) Pfam (PF15009) | Homo sapiens (Human) | hSTING, Endoplasmic reticulum interferon stimulator, ERIS, Mediator of IRF3 activation, hMITA, Transmembrane protein 173 |
| 2 | B (A) | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide | non-polymer | 658.4 | 1 | Chemie (2BA) | |||
| 3 | C (A) | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
| 4 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | E (A) | water | water | 18.0 | 51 | Chemie (HOH) |
Sequence modifications
A: 139 - 379 (UniProt: Q86WV6)
| PDB | External Database | Details |
|---|---|---|
| Ala 230 | Gly 230 | conflict |
| Arg 232 | His 232 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27137.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 819.6 | |
| All* | Total formula weight | 27957.2 |
