6CWJ
Crystal structures of cyanuric acid hydrolase from Moorella thermoacetica complexed with 1,3-Acetone Dicarboxylic Acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Cyanuric acid amidohydrolase | polymer | 363 | 38484.7 | 4 | UniProt (Q2RGM7) Pfam (PF09663) In PDB | Moorella thermoacetica (strain ATCC 39073 / JCM 9320) | CAH |
| 2 | A | MALONATE ION | non-polymer | 102.0 | 1 | Chemie (MLI) | |||
| 3 | A, B, C, D | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 4 | A, D | ACETATE ION | non-polymer | 59.0 | 4 | Chemie (ACT) | |||
| 5 | B, C, D | 3-oxopentanedioic acid | non-polymer | 146.1 | 3 | Chemie (6JN) | |||
| 6 | B | 1,3-PROPANDIOL | non-polymer | 76.1 | 1 | Chemie (PDO) | |||
| 7 | water | water | 18.0 | 592 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 362 (UniProt: Q2RGM7)
| PDB | External Database | Details |
|---|---|---|
| His 0 | - | expression tag |
| Ala 103 | Gln 103 | engineered mutation |
| Ala 104 | Glu 104 | engineered mutation |
| Ala 107 | Lys 107 | engineered mutation |
| Ile 279 | Leu 279 | engineered mutation |
| Arg 280 | Lys 280 | engineered mutation |
| Ser 281 | Phe 281 | engineered mutation |
| - | Cys 283 | deletion |
| - | Cys 284 | deletion |
| - | Pro 285 | deletion |
| - | Pro 286 | deletion |
| - | Ala 287 | deletion |
| Asp 283 | Glu 288 | engineered mutation |
| Met 285 | Leu 290 | engineered mutation |
| Asp 286 | Ala 291 | engineered mutation |
| Arg 287 | Lys 292 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 153938.6 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1012.9 | |
| All* | Total formula weight | 154951.5 |
