6CWA
CRYSTAL STRUCTURE PHGDH IN COMPLEX WITH NADH AND 3-PHOSPHOGLYCERATE AT 1.77 A RESOLUTION
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | D-3-phosphoglycerate dehydrogenase | polymer | 327 | 35055.3 | 2 | UniProt (O43175) Pfam (PF00389) Pfam (PF02826) In PDB | Homo sapiens (Human) | 3-PGDH,2-oxoglutarate reductase,Malate dehydrogenase |
2 | A, B | 3-PHOSPHOGLYCERIC ACID | non-polymer | 186.1 | 2 | Chemie (3PG) | |||
3 | A, B | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE | non-polymer | 665.4 | 2 | Chemie (NAI) | |||
4 | water | water | 18.0 | 311 | Chemie (HOH) |
Sequence modifications
A, B: 3 - 314 (UniProt: O43175)
PDB | External Database | Details |
---|---|---|
Ser -12 | - | expression tag |
Gly -11 | - | expression tag |
Val -10 | - | expression tag |
Asp -9 | - | expression tag |
Leu -8 | - | expression tag |
Gly -7 | - | expression tag |
Thr -6 | - | expression tag |
Glu -5 | - | expression tag |
Asn -4 | - | expression tag |
Leu -3 | - | expression tag |
Tyr -2 | - | expression tag |
Phe -1 | - | expression tag |
Gln 0 | - | expression tag |
Ser 1 | - | expression tag |
Met 2 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 70110.5 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1703.0 | |
All* | Total formula weight | 71813.5 |