6CW7
E. coli DHFR product complex with (6S)-5,6,7,8-TETRAHYDROFOLATE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dihydrofolate reductase | polymer | 165 | 18848.2 | 1 | UniProt (P0ABQ5) Pfam (PF00186) UniProt (by SIFTS) (P0ABQ4) | Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) | |
| 2 | B (A) | (6S)-5,6,7,8-TETRAHYDROFOLATE | non-polymer | 445.4 | 1 | Chemie (THG) | |||
| 3 | C, D, E (A) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 4 | F, G, H, I (A) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 5 | J (A) | water | water | 18.0 | 205 | Chemie (HOH) |
Sequence modifications
A: 1 - 159 (UniProt: P0ABQ5)
| PDB | External Database | Details |
|---|---|---|
| His 160 | - | expression tag |
| His 161 | - | expression tag |
| His 162 | - | expression tag |
| His 163 | - | expression tag |
| His 164 | - | expression tag |
| His 165 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18848.2 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 649.0 | |
| All* | Total formula weight | 19497.2 |
