6CW6

Structure of alpha-GC[8,18] bound by CD1d and in complex with the Va14Vb8.2 TCR

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Antigen-presenting glycoprotein CD1d1	polymer	285	32609.6	1	UniProt (P11609) Pfam (PF16497) Pfam (PF07654) In PDB	Mus musculus (Mouse)
2	B	Beta-2-microglobulin	polymer	99	11660.4	1	UniProt (P01887) Pfam (PF07654) In PDB	Mus musculus (Mouse)
3	C	Chimeric T cell antigen receptor alpha chain	polymer	209	23055.6	1	UniProt (K7N5M3) Pfam (PF07686) Pfam (PF09291) In PDB	Mus musculus (Mouse)
4	D	Chimeric T cell antigen receptor beta chain Vb8.2	polymer	241	27027.0	1	UniProt (K7N5M4) Pfam (PF07686) Pfam (PF07654) In PDB	Mus musculus (Mouse)
5	E	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	1	In PDB GlyTouCan (G21290RB)
6	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
7	A	(2S,3S,4R)-N-OCTANOYL-1-[(ALPHA-D-GALACTOPYRANOSYL)OXY]-2-AMINO-OCTADECANE-3,4-DIOL	non-polymer		605.8	1	Chemie (PBS)
8	A	PALMITIC ACID	non-polymer		256.4	1	Chemie (PLM)

Sequence modifications

A: 1 - 279 (UniProt: P11609)

PDB	External Database	Details
His 280	-	expression tag
His 281	-	expression tag
His 282	-	expression tag
His 283	-	expression tag
His 284	-	expression tag
His 285	-	expression tag

C: 0 - 113 (PDB: 6CW6)
C: 94 - 208 (UniProt: K7N5M3)
D: 0 - 129 (PDB: 6CW6)
D: 130 - 240 (UniProt: K7N5M4)

PDB	External Database	Details
Ser 186	Ala 194	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	94352.6
Branched	Number of molecules	1
	Total formula weight	570.5
Non-Polymers*	Number of molecules	4
	Total formula weight	1304.7
All*	Total formula weight	96227.8

*Water molecules are not included.