6CVU
Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with cytidine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | ATP-dependent dethiobiotin synthetase BioD | polymer | 235 | 23473.9 | 4 | UniProt (A5U2S7) Pfam (PF13500) UniProt (by SIFTS) (P9WPQ5) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | |
| 2 | E, F, H, I, K... (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 8 | Chemie (SO4) | |||
| 3 | G, J, M, P (A, B, C, D) | 4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE | non-polymer | 243.2 | 4 | Chemie (CTN) PubChem (16760387) PubChem (6175) PubChem (6253) PubChem (24729357) PubChem (25085165) PubChem (44264135) PubChem (44307610) PubChem (44356841) PubChem (45109772) PubChem (114682) PubChem (122948) PubChem (160696) PubChem (57764456) PubChem (57807005) PubChem (58460874) PubChem (58519508) PubChem (71230474) PubChem (59476533) PubChem (59713247) PubChem (60138999) PubChem (3013211) PubChem (66800112) PubChem (68199635) PubChem (453552) PubChem (54353063) PubChem (638040) PubChem (58899188) PubChem (1265901) PubChem (89495334) PubChem (596) PubChem (90089493) PubChem (70994952) PubChem (6480064) PubChem (5702244) PubChem (6476646) PubChem (6479885) PubChem (6551012) PubChem (6603781) PubChem (6713582) PubChem (117732781) PubChem (122468509) PubChem (12358851) PubChem (142117909) PubChem (148710634) PubChem (168266058) PubChem (171699434) | |||
| 4 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 313 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 226 (UniProt: A5U2S7)
| PDB | External Database | Details |
|---|---|---|
| Met -8 | - | initiating methionine |
| Gly -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Gly 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 93895.7 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1741.4 | |
| All* | Total formula weight | 95637.0 |
