6CVU
Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with cytidine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | ATP-dependent dethiobiotin synthetase BioD | polymer | 235 | 23473.9 | 4 | UniProt (A5U2S7) Pfam (PF13500) UniProt (by SIFTS) (P9WPQ5) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | |
| 2 | E, F, H, I, K... (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 8 | Chemie (SO4) | |||
| 3 | G, J, M, P (A, B, C, D) | 4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE | non-polymer | 243.2 | 4 | Chemie (CTN) | |||
| 4 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 313 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 226 (UniProt: A5U2S7)
| PDB | External Database | Details |
|---|---|---|
| Met -8 | - | initiating methionine |
| Gly -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Gly 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 93895.7 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1741.4 | |
| All* | Total formula weight | 95637.0 |
