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6CUA

Structure of human DNA polymerase beta complexed with 8-ClG in the template base paired with incoming non-hydrolyzable GTP and MANGANESE

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ADNA polymerase betapolymer33538241.71UniProt (P06746)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
In PDB
Homo sapiens (Human)
2TDNA (5'-D(*CP*CP*GP*AP*CP*(CGM)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3')polymer164878.61Homo sapiens
3PDNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3')polymer103085.01Homo sapiens
4DDNA (5'-D(P*GP*TP*CP*GP*G)-3')polymer51536.01Homo sapiens
5AMANGANESE (II) IONnon-polymer54.92Chemie (MN)
6ASODIUM IONnon-polymer23.02Chemie (NA)
7A2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosinenon-polymer506.21Chemie (XG4)
8waterwater18.0117Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight47741.3
Non-Polymers*Number of molecules5
Total formula weight662.1
All*Total formula weight48403.4
*Water molecules are not included.

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PDB entries from 2024-06-12

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