6CRM

Crystal Structure of RecQ catalytic core from C. sakazakii bound to an unfolded G-quadruplex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	RecQ	polymer	541	60445.3	1	UniProt (A7MQK9) Pfam (PF00270) Pfam (PF00271) Pfam (PF16124) Pfam (PF09382)	Cronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii)
2	B (B)	DNA (5'-D(P*GP*GP*GP*TP*CP*GP*GP*TP*GP*CP*CP*TP*TP*A)-3')	polymer	37	11570.4	1		synthetic construct
3	C (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
4	D, E (A, B)	water	water		18.0	142	Chemie (HOH)

Sequence modifications

A: 1 - 521 (UniProt: A7MQK9)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	72015.7
Non-Polymers*	Number of molecules	1
	Total formula weight	65.4
All*	Total formula weight	72081.1

*Water molecules are not included.