6CQQ
Crystal structure of F24 TCR -DR15-RQ13 peptide complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, F (A, F) | HLA class II histocompatibility antigen, DR alpha chain | polymer | 182 | 21185.9 | 2 | UniProt (P01903) Pfam (PF00993) Pfam (PF07654) | Homo sapiens (Human) | MHC class II antigen DRA |
| 2 | B, G (B, G) | HLA-DRB1 protein | polymer | 190 | 22073.6 | 2 | UniProt (D7RIH9) Pfam (PF00969) Pfam (PF07654) UniProt (by SIFTS) (P01911) | Homo sapiens (Human) | MHC class II antigen |
| 3 | C, H (C, H) | Peptide from Capsid protein p24 | polymer | 13 | 1600.8 | 2 | UniProt (P04591) UniProt (by SIFTS) (P04585) | HIV-1 M:B_HXB2R | Pr55Gag |
| 4 | D, I (D, I) | F24 alpha chain | polymer | 205 | 22801.2 | 2 | Pfam (PF07686) UniProt (by SIFTS) (A0A0B4J272) | Homo sapiens (Human) | |
| 5 | E, J (E, J) | F24 beta chain | polymer | 245 | 28084.3 | 2 | Pfam (PF07654) UniProt (by SIFTS) (A0A5B9) | Homo sapiens (Human) | |
| 6 | K, O, P (A, F, G) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 7 | L, M (B, C) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 8 | N (E) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 9 | Q (J) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 10 | AA, R, S, T, U... (J, A, B, C, D...) | water | water | 18.0 | 385 | Chemie (HOH) |
Sequence modifications
A, F: 1 - 182 (UniProt: P01903)
| PDB | External Database | Details |
|---|---|---|
| Thr 182 | Ala 207 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 191491.7 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 870.4 | |
| All* | Total formula weight | 192362.1 |
