6CQ4
TBK1 in Complex with Cyclohexyl Analog of Amlexanox
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase TBK1 | polymer | 660 | 76025.9 | 1 | UniProt (Q9UHD2) Pfam (PF00069) Pfam (PF18396) Pfam (PF18394) | Homo sapiens (Human) | NF-kappa-B-activating kinase,T2K,TANK-binding kinase 1 |
| 2 | B (A) | 2-amino-7-(4,4-difluorocyclohexyl)-5-oxo-5H-[1]benzopyrano[2,3-b]pyridine-3-carboxylic acid | non-polymer | 374.3 | 1 | Chemie (F8P) |
Sequence modifications
A: 1 - 657 (UniProt: Q9UHD2)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 76025.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 374.3 | |
| All* | Total formula weight | 76400.3 |
