6CQ1
BCL6 BTB domain in complex with 15a
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | B-cell lymphoma 6 protein | polymer | 131 | 14916.3 | 2 | UniProt (P41182) Pfam (PF00651) In PDB | Homo sapiens (Human) | BCL-6,B-cell lymphoma 5 protein,BCL-5,Protein LAZ-3,Zinc finger and BTB domain-containing protein 27,Zinc finger protein 51 |
2 | A, B | 2-{6-({[2-(1H-indol-3-yl)ethyl]carbamothioyl}amino)-3-[(4-methylpiperazin-1-yl)methyl]-1H-indol-1-yl}-N-(propan-2-yl)acetamide | non-polymer | 545.7 | 2 | Chemie (F8J) | |||
3 | water | water | 18.0 | 237 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 129 (UniProt: P41182)
PDB | External Database | Details |
---|---|---|
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Gln 8 | Cys 8 | engineered mutation |
Arg 67 | Cys 67 | engineered mutation |
Asn 84 | Cys 84 | engineered mutation |
Val 99 | Glu 99 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 29832.6 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 1091.5 | |
All* | Total formula weight | 30924.1 |