6CNL
Crystal Structure of H105A PGAM5 Dodecamer
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C, L, J, F... | Serine/threonine-protein phosphatase PGAM5, mitochondrial | polymer | 223 | 25407.9 | 12 | UniProt (Q96HS1) Pfam (PF00300) In PDB | Homo sapiens (Human) | Bcl-XL-binding protein v68,Phosphoglycerate mutase family member 5 |
2 | M, O, X, V, R... | PGAM5 Multimerization Motif Peptide | polymer | 14 | 1682.8 | 12 | Homo sapiens | ||
3 | C, E, P, L, J... | MAGNESIUM ION | non-polymer | 24.3 | 31 | Chemie (MG) | |||
4 | water | water | 18.0 | 199 | Chemie (HOH) |
Sequence modifications
A, C, L, J, F, H, K, D, B, I, G, E: 90 - 289 (UniProt: Q96HS1)
PDB | External Database | Details |
---|---|---|
Met 67 | - | initiating methionine |
His 68 | - | expression tag |
His 69 | - | expression tag |
His 70 | - | expression tag |
His 71 | - | expression tag |
His 72 | - | expression tag |
His 73 | - | expression tag |
Ser 74 | - | expression tag |
Ser 75 | - | expression tag |
Gly 76 | - | expression tag |
Val 77 | - | expression tag |
Asp 78 | - | expression tag |
Leu 79 | - | expression tag |
Gly 80 | - | expression tag |
Thr 81 | - | expression tag |
Glu 82 | - | expression tag |
Asn 83 | - | expression tag |
Leu 84 | - | expression tag |
Tyr 85 | - | expression tag |
Phe 86 | - | expression tag |
Gln 87 | - | expression tag |
Ser 88 | - | expression tag |
Met 89 | - | expression tag |
Ala 105 | His 105 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 24 |
Total formula weight | 325088.1 | |
Non-Polymers* | Number of molecules | 31 |
Total formula weight | 753.5 | |
All* | Total formula weight | 325841.6 |