6CN6
RORC2 LBD complexed with compound 34
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Nuclear receptor ROR-gamma | polymer | 259 | 29935.4 | 1 | UniProt (P51449) Pfam (PF00104) In PDB | Homo sapiens (Human) | Nuclear receptor RZR-gamma,Nuclear receptor subfamily 1 group F member 3,RAR-related orphan receptor C,Retinoid-related orphan receptor-gamma |
| 2 | A | 3-cyano-N-{3-[1-(cyclopentanecarbonyl)piperidin-4-yl]-1,4-dimethyl-1H-indol-5-yl}benzamide | non-polymer | 468.6 | 1 | Chemie (F7J) | |||
| 3 | water | water | 18.0 | 91 | Chemie (HOH) |
Sequence modifications
A: 259 - 517 (UniProt: P51449)
| PDB | External Database | Details |
|---|---|---|
| Ser 278 | Cys 278 | engineered mutation |
| Ser 345 | Cys 345 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29935.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 468.6 | |
| All* | Total formula weight | 30404.0 |
