6CN2
Crystal structure of zebrafish Phosphatidylinositol-4-phosphate 5- kinase alpha isoform D236N with bound ATP/Ca2+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | polymer | 394 | 44868.3 | 1 | UniProt (Q503I3) Pfam (PF01504) | Danio rerio (Zebrafish) | Phosphatidylinositol-4-phosphate 5-kinase,type I,alpha,a |
| 2 | B (A) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 3 | C, D (A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 4 | E (A) | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
A: 49 - 431 (UniProt: Q503I3)
| PDB | External Database | Details |
|---|---|---|
| Met 46 | - | initiating methionine |
| Ala 47 | - | expression tag |
| Ser 48 | - | expression tag |
| Asn 236 | Asp 236 | engineered mutation |
| Leu 432 | - | expression tag |
| Glu 433 | - | expression tag |
| His 434 | - | expression tag |
| His 435 | - | expression tag |
| His 436 | - | expression tag |
| His 437 | - | expression tag |
| His 438 | - | expression tag |
| His 439 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 44868.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 587.3 | |
| All* | Total formula weight | 45455.7 |
